Glucosamine - Functionalized Gold Nanoparticles (GlcN-AuNPs): Sintesis Dan Stabilitas

Prayoga, Galuh Agita (2024) Glucosamine - Functionalized Gold Nanoparticles (GlcN-AuNPs): Sintesis Dan Stabilitas. Other thesis, Institut Teknologi Sepuluh Nopember.

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Abstract

Glucosamine-Functionalized Gold Nanoparticles (GlcN-AuNPs) berhasil disintesis pada penelitian ini. Glukosamin dipilih karena diprediksi dapat berinteraksi dengan permukaan nanopartikel emas (AuNPs) yang kemudian mampu menghambat terjadinya proses aglomerasi maupun agregasi. Hal ini memungkinkan AuNPs menjadi lebih stabil. Untuk memaksimalkan stabilitas, sintesis nanopartikel dilakukan dengan proses sonikasi. Setelah itu, pengaruh konsentrasi glukosamin dan proses sonikasi terhadap stabilitas nanopartikel dipantau dengan spektrofotometer UV-Vis hingga hari ke-30 dan dianalisis menggunakan Two-Way Anova. Didapatkan bahwa konsentrasi penambahan glukosamin tidak mempengaruhi stabilitas AuNPs secara signifikan. Akan tetapi, variasi perbandingan mol Au:GlcN = 1:1 dinilai paling stabil. Kemudian, proses sonikasi memiliki pengaruh yang signifikan terhadap stabilitas AuNPs, dimana AuNPs yang disintesis dengan proses sonikasi lebih stabil dibandingkan AuNPs yang disintesis tanpa pengaruh sonikasi.
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Glucosamine-Functionalized Gold Nanoparticles (GlcN-AuNPs) were successfully synthesized in this research. Glucosamine was chosen because it is predicted to be able to interact with the surface of gold nanoparticles (AuNPs) which is then able to inhibit the agglomeration and aggregation processes. This allows the AuNPs to be more stable. To maximize stability, nanoparticle synthesis was carried out using a sonication process. After that, the effect of glucosamine concentration and the sonication process on the stability of the nanoparticles was monitored using a UV-Vis spectrophotometer until the 30th day and analyzed using Two-Way Anova. It was found that the added concentration of glucosamine did not significantly affect the stability of AuNPs. However, the Au:GlcN = 1:1 mole ratio variation is considered the most stable. Then, the sonication process has a significant influence on the stability of AuNPs, where AuNPs synthesized using the sonication process are more stable than AuNPs synthesized without the influence of sonication.

Item Type:	Thesis (Other)
Uncontrolled Keywords:	Glukosamin, Nanopartikel Emas, Sonikasi, Stabilitas, Glucosamine, Gold Nanoparticles, Sonication, Stability
Subjects:	T Technology > TP Chemical technology > TP248 Nanogels. Nanoparticles.
Divisions:	Faculty of Science and Data Analytics (SCIENTICS) > Chemistry > 47201-(S1) Undergraduate Thesis
Depositing User:	Galuh Agita Prayoga
Date Deposited:	14 Mar 2024 02:29
Last Modified:	14 Mar 2024 02:29
URI:	http://repository.its.ac.id/id/eprint/107440

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