Istiqoma, Siti Mualimatul (2024) Diversifikasi Ekstrak Metanol Daun Moringa oleifera Sebagai Suplemen Makanan Bernutrisi Dengan Sediaan Chewable Gummy Tablets (CGTs). Other thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Moringa oleifera memiliki kandungan nutrisi esensial seperti protein, vitamin, mineral, karbohidrat, dan fitokimia lain yang telah dimanfaatkan oleh masyarakat untuk obat tradisional. Kandungan senyawa metabolit sekunder pada daun M. oleifera telah dipelajari dengan berbagai metode isolasi, salah satunya metode ekstraksi. Aktivitas penghambatan α-glukosidase pada daun ekstrak metanol menunjukkan persentase tertinggi di antara ekstrak lain. Oleh karena itu, daun M. oleifera memiliki potensi untuk dapat dimanfaatkan sebagai produk makanan seperti suplemen dalam sediaan tablet, kapsul, atau pil. Namun, suplemen makanan sediaan tablet, kapsul, atau pil tersebut tidak sesuai untuk orang-orang yang mengalami masalah disfagia atau kesulitan dalam menelan sehingga dikembangkan bentuk sediaan lain berupa Chewable Gummy Tablets (CGTs) untuk memudahkan proses menelan bagi beberapa orang. Pada penelitian ini, CGTs dibuat menggunakan gelatin dan Gom Arab (GA) yang telah digunakan secara luas pada industri makanan. Penggunaan variasi konsentrasi gelatin : GA menghasilkan perbedaan pada kondisi fisikokimia pada CGTs. Variasi formulasi gelatin : GA yang digunakan ada 3 yaitu formula 1 (2:1), formula 2 (1:1), dan formula 3 (1:2). Formula 3 memiliki nilai tertinggi pada analisis swelling ratio sebesar 3,5816 ± 0,1370%. Formula 1 memiliki nilai analisis sineresis terendah sebesar 4,7070 ± 0,1066%. Nilai analisis waktu dispersi dan hardness formula 1 merupakan yang tertinggi sebesar 6,9333 ± 0,1528 menit dan 0,5600 ± 0,2200 N dibandingkan formula lainnya.
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Moringa oleifera has been used as a traditional medicine by communities because it contains essential nutrients like proteins, vitamins, minerals, carbohydrates, and phytochemicals. The optional metabolite intensifies in M. oleifera leaves have been concentrated on utilizing different seclusion strategies, including extraction techniques. Methanol leaf extracts have the highest percentage of α-glucosidase inhibition activity of any extract. As a result, the leaves of M. oleifera could be used to make food or supplements in tablet, capsule, or pill form. Be that as it may, these structures may not be appropriate for people encountering dysphagia or trouble gulping, prompting the advancement of elective structures like Chewable Gummy Tablets (CGTs) to ease gulping for certain people. Gelatin and Gum Arabic (GA), two commonly used ingredients in the food industry, were used to make CGTs in this study. Shifting centralizations of gelatin:GA brought about contrasts in the physicochemical properties of CGTs. There were three different formulas: formula 1 (2:1), formula 2, and formula 3. When compared to formulations 1 and 2, formula 3 had the highest values in the swelling ratio test 3.5816 ± 0.1370%. Formula 1 had the highest values in syneresis test 4.7070 ± 0.1066%. When compared to the other formulas, formula 1 had the highest dispersion time and hardness tests, with 6.9333 ± 0.1528 minutes and 0.5600 ± 0.2200 N, respectively.
Item Type: | Thesis (Other) |
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Uncontrolled Keywords: | Chewable Gummy Tablets (CGTs), Gelatin, Gom Arab, Moringa oleifera, Texture Analyzer, Gelatine, Gum Arabic |
Subjects: | Q Science > QD Chemistry Q Science > QD Chemistry > QD251.2 Chemistry, Organic. Biochemistry |
Divisions: | Faculty of Science and Data Analytics (SCIENTICS) > Chemistry > 47201-(S1) Undergraduate Thesis |
Depositing User: | Siti Mualimatul Istiqomah |
Date Deposited: | 16 Aug 2024 02:36 |
Last Modified: | 16 Aug 2024 02:36 |
URI: | http://repository.its.ac.id/id/eprint/114183 |
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