Amalia, Yufi Rizky (2025) Bolus Cetak Tiga Dimensi Untuk Terapi Kankerpayudara Non Mastektomi Kiri Dengan Teknik Intensity-Modulated Radiation Therapy (LMRT). Other thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Perawatan radioterapi memiliki tujuan untuk menghancurkan sel-sel kanker dengan memfokuskan penyinaran pada target volume agar dosis yang diterima maksimal dan meminimalkan dosis yang diterima pada Organ at Risk (OARs). Pada tugas akhir ini perencanaan perawatan radioterapi dilakukan menggunakan fantom antropomorfik dengan kasus kanker payudara sebelah kiri menggunakan teknik Intensity-Modulated Radiation Therapy (IMRT) 4 lapangan dengan dosis preskripsi 5000 cGy. Untuk meningkatkan dosis permukaan mengurangi efek skin-sparing maka digunakan bolus cetak tiga dimensi dengn ketebalan 1 cm berbahan silicon rubber, silicon rubber dengan penambahan bismuth(iii) nitrate, PLA, dan PETG yang dicetak menggunakan teknologi 3D printing agar lebih sesuai dengan kontur anatomi pasien. Penelitian ini mengevaluasi bolus adaptif melalui uji densitas dengan membandingkan densitas elektron relatif terhadap jaringan lunak menggunakan CT-Scan. Pengaplikasian klinis menggunakan Linear Accelerator dengan sumber foton 6 MV dan film gafchromic EBT4 sebagai detektor guna memastikan kesesuaian perencanaan dosis. Hasil penelitian menunjukkan bahwa bolus cetak tiga dimensi pada semua material memiliki densitas elektron mendekati jaringan lunak dengan celah udara terendah tercapai pada bolus silicon rubber dengan penambahan bismuth(iii) nitrate yakni 0,15 cm namun tidak memiliki perbedaan signifikan terhadap bolus material lain. Selain itu, hasil dosis perencanaan dan verifikasi yang dilakukan tidak memiliki perbedaan signifikan antara tanpa bolus dan dengan bolus. Namun, pada parameter penilaian CI dan HI dengan bolus memiliki nilai ideal daripada tanpa bolus.
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Radiotherapy aims to destroy cancer cells by focusing radiation on the target volume to maximize the dose received and minimize the dose received on Organs at Risk (OARs). In this final project, radiotherapy treatment planning was carried out using an anthropomorphic phantom with a left breast cancer case using the 4-field Intensity-Modulated Radiation Therapy (IMRT) technique with a prescription dose of 5000 cGy. To increase the surface dose and reduce the skin-sparing effect, a three-dimensional printed bolus with a thickness of 1 cm was used, made of silicon rubber, silicon rubber with the addition of bismuth(iii) nitrate, PLA, and PETG printed using 3D printing technology to better fit the patient's anatomical contours. This study evaluated the adaptive bolus through a density test by comparing the electron density relative to soft tissue using a CT-Scan. The clinical application uses a Linear Accelerator with a 6 MV photon source and EBT4 Gafchromic film as a detector to ensure the suitability of dose planning. The results of the study showed that the three-dimensional printed bolus on all materials was close to that of soft tissue, with the lowest air gap achieved in the silicon rubber bolus with the addition of Bismuth (iii) nitrate (0.15 cm). However, this was not significantly different from that of the other materials. In addition, the results of the dose planning and verification did not show a significant difference between the bolus and no bolus groups. However, the CI and HI assessment parameters with the bolus had ideal values compared to those without the bolus.
| Item Type: | Thesis (Other) |
|---|---|
| Uncontrolled Keywords: | Aplikasi Klinis, Bolus, Film EBT4, Distribusi Dosis, Radioterapi. Application, Bolus, EBT4 Film, Dose Distribution, Radiotherapy. |
| Subjects: | Q Science > QC Physics > QC795.5 Radioactivity and radioactive Instruments and apparatus (General) |
| Divisions: | Faculty of Science and Data Analytics (SCIENTICS) > Physics > 45201-(S1) Undergraduate Thesis |
| Depositing User: | Yufi Rizky Amalia |
| Date Deposited: | 22 Jul 2025 10:25 |
| Last Modified: | 23 Jul 2025 01:27 |
| URI: | http://repository.its.ac.id/id/eprint/120573 |
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