Evaluasi Kelayakan Dan Durabilitas Fantom Gelatin - Gliserin Untuk Elastografi Ultrasound

Kamaludin, Nabil Arsy Muhamad (2025) Evaluasi Kelayakan Dan Durabilitas Fantom Gelatin - Gliserin Untuk Elastografi Ultrasound. Other thesis, Institut Teknologi Sepuluh Nopember.

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Abstract

Ultrasonografi (US) merupakan alat pencitraan yang banyak digunakan karena sifatnya non-invasif, real-time, dan biaya relative terjangkau. US memiliki mode B yang dapat digunakan untuk mendapatkan citra anatomi jaringan dan mode Strain elastography digunakan untuk mengetahui kekakuan jaringan. Pencitraan US dapat digunakan sebagai diagnostik secara berkala atau rutin. Oleh karena itu, perlu memastikan bahwa alat US memiliki akurasi dan reproduktibiltas yang tinggi dalam merepresentasikan jaringan pada setiap penggunaan melalui kontrol kualitas menggunakan fantom. Fantom komersial yang sering digunakan pada pengujian kualitas kontrol memiliki harga yang relatif mahal. Oleh sebab itu, dilakukan penelitian pembuatan fantom berbahan dasar gelatin-gliserin dengan konsentrasi gelatin 7,5%. Dan gliserin 92,5%. Pengujian densitas menggunakan perbandingan massa terhadap volume, pengujian modulus elastisitas geser dan estimasi viskoelastis menggunakan Dynamic Mechanical Analyzer (DMA), pengujian keseragaman citra dan jarak menggunakan mode B (US), serta pengujian rasio regangan menggunakan mode strain elastography (SE). Didapatkan grafik hubungan linear antara gaya dengan pergeseran, yang mempunyai pergeseran 1,2×10⁸ μm pada gaya maksimal 6,5×10⁴ N, karena benda mencapai batas untuk bergeser. Sementara itu, estimasi modulus geser 〖(m〗_0), viskositas (m_a) dan orde fractional α berurutan sebesar 1,85 kPa, 0,604 kPa.s dan 0,610 menandakan fantom pada wilayah viskos. Serta densitas dari fantom gelatin 7,5% mengalami kenaikan pada fantom homogen sebesar 3,9% dan heterogen sebesar 0,78% dari densitas awal. Hasil citra menjelaskan bahwa distribusi nilai piksel dari 6 minggu mengalami konsistensi distribusi yang cukup baik ditandai dengan distribusi nilai piksel yang memiliki tren serupa antara minggu pertama hingga minggu keenam dan pada pengujian jarak citra nilon yang dihasilkan sudah lolos uji karena tidak melewati batas toleransi maksimal ± 0,15 cm untuk pengukuran jarak vertikal dan ± 0,2 cm untuk pengukuran jarak horizontal. Nilai strain ratio pada fantom homogen dengan nilai p value lebih dari 0,05, Dimana menandakan bahwa fantom homogen memiliki nilai strain elastography cukup konsisten dari minggu pertama sampai minggu keenam.
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Ultrasonography (US) is a widely used imaging tool due to its non-invasive nature, real-time capability, and relatively affordable cost. US has B-mode which can be used to obtain anatomical tissue images and strain elastography mode is used to determine tissue stiffness. US imaging can be used for periodic or routine diagnostics. Therefore, it is necessary to ensure that the US equipment has high accuracy and reproducibility in representing tissues in each use through quality control using phantoms. Commercial phantoms commonly used in quality control testing are relatively expensive. Therefore, research was conducted to create phantoms made from gelatin-glycerin base materials with a gelatin concentration of 7.5% and glycerin 92.5%. Density testing used mass-to-volume ratio, shear elastic modulus testing and viscoelastic estimation using Dynamic Mechanical Analyzer (DMA), image uniformity and distance testing using B-mode (US), and strain ratio testing using strain elastography (SE) mode. A linear relationship graph between force and displacement was obtained, which had a displacement of 1.2×10⁸ μm at maximum force of 6.5×10⁴ N, because the object reached its limit for displacement. Meanwhile, the estimated shear modulus, viscosity, and fractional order α were 1.85 kPa, 0.604 kPa.s, and 0.610 respectively, indicating the phantom was in the viscous region. The density of the 7.5% gelatin phantom increased in homogeneous phantoms by 3.9% and heterogeneous phantoms by 0.78% from the initial density. The image results explained that the pixel value distribution over 6 weeks showed fairly good distribution consistency, indicated by pixel value distributions having similar trends from the first week to the sixth week, and in nylon image distance testing, the results passed the test because they did not exceed the maximum tolerance limits of ± 0.15 cm for vertical distance measurements and ± 0.2 cm for horizontal distance measurements. The strain ratio values in homogeneous phantoms had p-values greater than 0.05, indicating that homogeneous phantoms had fairly consistent strain elastography values from the first week to the sixth week

Item Type:	Thesis (Other)
Uncontrolled Keywords:	Densitas, DMA, Elastisitas, Strain Ratio, Density, DMA, Elasticity, Strain Ratio.
Subjects:	R Medicine > R Medicine (General) R Medicine > R Medicine (General) > R857.M3 Biomedical materials. Biomedical materials--Testing. R Medicine > RC Internal medicine > RC78 Diagnosis, Radioscopic--Examinations, questions, etc. R Medicine > RC Internal medicine > RC78.7.U4 Ultrasonic imaging.
Divisions:	Faculty of Mathematics and Science > Physics > 45201-(S1) Undergraduate Thesis
Depositing User:	Nabil Arsy Muhamad Kamaludin
Date Deposited:	31 Jul 2025 03:22
Last Modified:	31 Jul 2025 03:22
URI:	http://repository.its.ac.id/id/eprint/124677

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