CMC/CS/SA Terimpregnasi Ag Dan ZnO Sebagai Agen Antibakteri Untuk Aplikasi Wound Dressing Dengan Metode Ultrasonikasi

Kayana, Nari Dzakirah and Sakinah, Kania Putri (2025) CMC/CS/SA Terimpregnasi Ag Dan ZnO Sebagai Agen Antibakteri Untuk Aplikasi Wound Dressing Dengan Metode Ultrasonikasi. Other thesis, Institut Teknologi Sepuluh Nopember.

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Abstract

Luka merupakan degradasi jaringan epitel akibat cedera atau pembedahan. Prevalensi cedera di Indonesia mencapai 9,2%, dengan 64,1% luka lecet/memar dan 20,1% luka robek/sayat. Metode pengobatan konvensional saat ini seperti kapas dan plester memiliki kemanjuran terbatas, sementara kasa basah dapat mengering dan menempel pada luka, mengganggu keseimbangan kelembaban. Kombinasi material Wound Dressing memberikan solusi untuk mempercepat penyembuhan luka serta memiliki sifat biokompabilitas yang baik. Oleh karena itu, penelitian ini mengkaji kombinasi material Carboxymethyl Cellulose/Chitosan/Sodium Alginate (CMC/CS/SA) dengan penambahan Ag dan ZnO sebagai agen antibakteri untuk aplikasi wound dressing. Tujuannya adalah mengetahui karakteristik dan sifat antibakteri kombinasi material CMC/CS/SA terimpregnasi Ag dan ZnO untuk aplikasi wound dressing menggunakan metode ultrasonikasi probe. Berikutnya material CMC/CS/SA terimpregnasi Ag dan ZnO dikarakterisasi dengan FTIR, XRD, SEM, swelling ratio, dan uji aktivitas bakteri.
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Wounds are the degradation of epithelial tissue due to injury or surgery. The prevalence of injuries in Indonesia is 9.2%, with 64.1% of wounds being abrasions/bruises and 20.1% being lacerations/cuts. Current conventional treatment methods such as cotton and plaster have limited efficacy, while wet gauze can dry out and stick to the wound, disrupting the moisture balance. Wound dressing material combinations provide a solution to accelerate wound healing and have good biocompatibility properties. Therefore, this study examines the combination of Carboxymethyl Cellulose/Chitosan/Sodium Alginate (CMC/CS/SA) materials with the addition of Ag and ZnO as antibacterial agents for wound dressing applications. The aim is to determine the characteristics and antibacterial properties of Ag- and ZnO-impregnated CMC/CS/SA material combinations for wound dressing applications using the probe ultrasonication method. Next, the Ag- and ZnO-impregnated CMC/CS/SA material was characterized by FTIR, XRD, SEM, swelling ratio, and bacterial activity test.

Item Type:	Thesis (Other)
Uncontrolled Keywords:	Antibakteri, CMC/CS/SA, Ultrasonikasi Probe, Pembalut Luka
Subjects:	T Technology > TP Chemical technology > TP1140 Polymers T Technology > TP Chemical technology > TP248.65.C55 Chitosan--Biotechnology.
Divisions:	Faculty of Vocational > Industrial Chemical Engineering
Depositing User:	Nari Dzakirah Kayana
Date Deposited:	04 Aug 2025 02:42
Last Modified:	04 Aug 2025 02:42
URI:	http://repository.its.ac.id/id/eprint/124851

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