Mahardika, Satriya Apta (2025) Studi Eksperimental Pengaruh Konfigurasi Parameter Cetak Direct Ink Writing (DIW) 3D Printing Menggunakan Tinta Komposit Polikaprolakton (PCL)/Hidroksiapatit (HA). Other thesis, Institut Teknologi Sepuluh Nopember.
![[thumbnail of 5007211178-Undergraduate_Thesis.pdf]](http://repository.its.ac.id/style/images/fileicons/text.png) |
Text
5007211178-Undergraduate_Thesis.pdf - Accepted Version Restricted to Repository staff only Download (4MB) | Request a copy |
Abstract
Menurut Data Riset Kesehatan Dasar Indonesia 2018, fraktur tulang merupakan cedera yang paling sering dialami pada posisi keempat di Indonesia. Pada kondisi fraktur tulang yang kehilangan massa tulang, maka salah satu upaya penyembuhannya adalah dengan implementasi bone scaffold agar terjadi proliferasi sel osteoinduksi. Material bone scaffolding harus memiliki biokompabilitas, biodegradabilitas, dan mampu menahan beban selama proses penyembuhan tulang. Salah satu metode pembuatan bone scaffolding yang saat ini sedang banyak diteliti adalah dengan menggunakan 3D printing berbahan komposit Hidroksiapatit (HA)/Polikaprolakton (PCL). Pada penelitian ini, Direct Ink Writing (DIW) 3D printing digunakan untuk membentuk bone scaffolding. Konfigurasi parameter cetak (nozzle diameter dan print speed) yang sesuai untuk DIW 3D Printing bone scaffold harus dicari agar hasil cetakan sesuai dengan standar ASTM D792, C830, dan D695.
Sintesis tinta bio (bioink) dengan rasio PCL:HA (1:1,5) berpelarut aseton dilakukan untuk memperoleh shape fidelity tinta bio yang memenuhi persyaratan untuk dapat dicetak dengan DIW 3D printing. Selanjutnya pengaruh nozzle diameter (1,2 mm, 1,3 mm, dan 1,4 mm) dan print speed (7,5 mm/s, 10 mm/s, dan 12,5 mm/s) diteliti untuk melihat pengaruh terhadap hasil cetak DIW 3D printing. Spesimen yang dicetak yaitu berbentuk silinder dengan diameter dan tinggi 28 mm selanjutnya dikarakterisasi dimensional stability, uji XRD dan FT-IR, dihitung densitas dan porositasnya, serta diuji sifat mekaniknya dengan uji tekan.
Hasil pengujian tinta PCL:HA menunjukkan nilai rata-rata viskositas 12866,518 ± 271,915 cP dengan shape fidelity yang baik. Sampel yang dicetak DIW 3D printing dengan konfigurasi nozzle diameter 1,2 mm dan print speed 12,5 mm/s menunjukkan hasil optimal dengan dimensional stability volumetric sebesar 17048,273 ± 162,169 mm3, densitas 1,163 ± 0,010 gr/cm3, dan porositas 3,718 ± 1,098%. Hasil uji mekanik kompresi memberikan compression strength sebesar 4,219 ± 0,058 MPa dan compression modulus sebesar 26,021 ± 0,541 MPa. Uji XRD dan FT-IR mengkonfirmasi bahwa material PCL:HA tidak mengalami perubahan fasa. Pada uji SEM, tampak bahwa hidroksiapatit telah telah terdistribusi secara homogen, namun terbentuknya void pada antar layer 3D printing tidak dapat dihindari. Hasil penelitian menunjukkan potensi DIW 3D printing diimplementasi dalam proses produksi bone scaffolding walaupun optimalisasi porositas yang sesuai dengan persyaratan standar bone scaffolding masih harus dilakukan.
=========================================================================================================================================
According to the 2018 Indonesian Basic Health Research Data, bone fractures are the fourth most common injury in Indonesia. In cases of bone fractures that result in loss of bone mass, one treatment option is the implementation of bone scaffolds to promote osteoinduction cell proliferation. Bone scaffolding materials must be biocompatible, biodegradable, and able to withstand loads during the bone healing process. One method of bone scaffolding fabrication currently being widely researched is 3D printing using a hydroxyapatite (HA)/polycaprolactone (PCL) composite. In this study, Direct Ink Writing (DIW) 3D printing was used to create the bone scaffolds. The appropriate print parameter configuration (nozzle diameter and print speed) for DIW 3D printing of bone scaffolds must be determined to ensure prints meet ASTM D792, C830, and D695 standards.
Bioink synthesis with a PCL:HA ratio (1:1.5) using acetone solvent was carried out to obtain shape fidelity that meets the requirements for DIW 3D printing. Furthermore, the influence of nozzle diameter (1.2 mm, 1.3 mm, and 1.4 mm) and print speed (7.5 mm/s, 10 mm/s, and 12.5 mm/s) on DIW 3D printing results was studied. The printed specimens, which were cylindrical in shape with a diameter and height of 28 mm, were then characterized for dimensional stability, XRD and FT-IR tests, density and porosity measurements, and mechanical properties were tested using a compression test.
The test results for PCL:HA ink showed an average viscosity of 12,866.518 ± 271.915 cP with good shape fidelity. The DIW 3D printed samples with a nozzle configuration of 1.2 mm diameter and a print speed of 12.5 mm/s showed optimal results with a volumetric dimensional stability of 17048.273 ± 162.169 mm3, a density of 1.163 ± 0.010 gr/cm3, and a porosity of 3.718 ± 1.098%. The results of the mechanical compression test provided a compression strength of 4.219 ± 0.058 MPa and a compression modulus of 26.021 ± 0.541 MPa. XRD and FT-IR tests confirmed that the PCL:HA material did not experience phase changes. In the SEM test, it appears that hydroxyapatite has been distributed homogeneously, but the formation of voids between 3D printing layers cannot be avoided. The results of this study indicate the potential of DIW 3D printing to be implemented in the bone scaffolding production process, although optimization of porosity in accordance with standard bone scaffolding requirements still needs to be done.
| Item Type: | Thesis (Other) |
|---|---|
| Uncontrolled Keywords: | Bone Scaffolding, DIW 3D Print, Hidroksiapatit, Polikaprolakton, Bone Scaffolding, DIW 3D Print, Hydroxiapatite, Policaprolactone |
| Subjects: | R Medicine > R Medicine (General) R Medicine > R Medicine (General) > R857.M3 Biomedical materials. Biomedical materials--Testing. T Technology > T Technology (General) T Technology > TP Chemical technology > TP1140 Polymers |
| Divisions: | Faculty of Civil Engineering and Planning > Geomatics Engineering |
| Depositing User: | Satriya Apta Mahardika |
| Date Deposited: | 01 Aug 2025 08:38 |
| Last Modified: | 01 Aug 2025 08:38 |
| URI: | http://repository.its.ac.id/id/eprint/125851 |
Actions (login required)
 |
View Item |