Jannah, Hanifah Hanindita (2025) Deteksi Parasetamol Menggunakan Screen Printed Carbon Electrode (SPCE) Termodifikasi Polipirol. Other thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Deteksi parasetamol telah dilakukan menggunakan Screen Printed Carbon Electrode (SPCE) yang termodifikasi polipirol. Polipirol dibuat dengan mencampurkan pirol dan FeCl3 sebagai agen pengoksidasi. Polipirol yang telah terbentuk diteteskan sebanyak 10 µL ke permukaan elektroda kerja SPCE dan dikeringkan selama 5 jam. SPCE termodifikasi polipirol dikarakterisasi menggunakan SEM-EDX. Evaluasi kinerja elektroda dilakukan menggunakan teknik voltametri siklik dengan rentang potensial -0,6 V hingga 0,8 V pada suhu ruang. Pengujian dilakukan dengan meneteskan larutan parasetamol sebanyak 100 µL ke atas permukaan elektroda. Hasil yang diperoleh menunjukkan SPCE termodifikasi polipirol memiliki luas permukaan yang lebih besar dibandingkan SPCE tanpa modifikasi. Interaksi antara parasetamol dengan permukaan elektroda dikontrol oleh proses difusi dan adsorpsi. SPCE termodifikasi polipirol memiliki limit deteksi sebesar 0,015 mM pada rentang linearitas 0 hingga 0,8 mM. SPCE termodifikasi polipirol menunjukkan sensitivitas yang cukup baik yaitu sebesar 418,747 µA/mM.cm2. Hasil uji interferensi menunjukkan bahwa SPCE termodifikasi polipirol selektif terhadap parasetamol dan memiliki stabilitas yang sangat baik (nilai %RSD 1,38% untuk puncak oksidasi dan 0,73% untuk puncak reduksi). Data penelitian tersebut menunjukkan bahwa SPCE termodifikasi polipirol memiliki kinerja yang sangat baik dan dapat digunakan untuk mendeteksi parasetamol dengan konsentrasi yang rendah.
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Paracetamol detection was performed using a Screen Printed Carbon Electrode (SPCE) modified with polypyrole. Polypyrole was prepared by mixing pyrole and FeCl3 as an oxidising agent. The formed polypyrole was dropped onto the working electrode surface of the SPCE at a volume of 10 µL and dried for 5 hours. The polypyrole-modified SPCE was characterised using SEM-EDX. Electrode performance evaluation was conducted using cyclic voltammetry with a potential range of -0.6 V to 0.8 V at room temperature. The test was conducted by dispensing 100 µL of paracetamol solution onto the electrode surface. The results showed that the polypyrrole-modified SPCE had a larger surface area compared to the unmodified SPCE. The interaction between paracetamol and the electrode surface was controlled by diffusion and adsorption processes. The polypyrole-modified SPCE had a detection limit of 0.015 mM in the linearity range of 0 to 0.8 mM. The polypyrole-modified SPCE showed good sensitivity of 418.747 µA/mM.cm². Interference test results indicate that the polypyrole-modified SPCE is selective for paracetamol and exhibits excellent stability (RSD values of 1.38% for the oxidation peak and 0.73% for the reduction peak). The research data demonstrate that the polypyrole-modified SPCE has excellent performance and can be used to detect paracetamol at low concentrations.
Item Type: | Thesis (Other) |
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Uncontrolled Keywords: | Parasetamol, Polipirol, Screen Printed Carbon Electrode, Sensor elektrokimia, Voltametri siklik Cyclic voltammetry, Electrochemical sensors, Paracetamol, Polypyrrole, Screen Printed Carbon Electrode |
Subjects: | Q Science Q Science > QD Chemistry Q Science > QD Chemistry > QD115 Electrochemical analysis Q Science > QD Chemistry > QD553 Electrochemistry. Electrolysis |
Divisions: | Faculty of Science and Data Analytics (SCIENTICS) > Chemistry > 47201-(S1) Undergraduate Thesis |
Depositing User: | Hanifah Hanindita Jannah |
Date Deposited: | 06 Aug 2025 04:07 |
Last Modified: | 06 Aug 2025 04:07 |
URI: | http://repository.its.ac.id/id/eprint/127728 |
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