Evaluasi Dosis Serap Pada Kasus Kanker Orofaring Menggunakan 3D Printed Head−Neck Phantom Dengan Teknik IMRT 6 MV

Marufah, Asmaul Lutfi (2022) Evaluasi Dosis Serap Pada Kasus Kanker Orofaring Menggunakan 3D Printed Head−Neck Phantom Dengan Teknik IMRT 6 MV. Other thesis, Institut Teknologi Sepuluh Nopember.

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Abstract

Perencanaan radioterapi pada kanker orofaring telah dilakukan menggunakan Teknik Intensity Modulated Radiotherapy (IMRT) 6MV. Penelitian ini memiliki tujuan untuk mengevaluasi dosis serap target dan organ at risk, evaluasi nilai Homogeneity Index (HI) dan Conformity Index (CI), evaluasi perbedaan dosis dari Treatment planning System (TPS) dan hasil pengukuran menggunakan film EBT3. Perencanaan IMRT dilakukan menggunakan software Eclipse pada 3D Printed Head-Neck Phantom dengan dosis 200 cGy, jumlah fraksinasi 30 dan jumlah lapangan yaitu 5,7, dan 9. Dosis serap target 9 lapangan memiliki dosis yang lebih mencakupi daerah PTV dibandingkan dengan 7 lapangan dan 5 lapangan. Dosis serap pada organ at risk menggunakan 5 lapangan menerima dosis yang lebih besar dibandingkan lapangan lainnya. Nilai HI yang diterima pada variasi 5, 7 dan 9 lapangan berturut−turut 0,0697; 0,0753; dan 0,0705. Nilai HI mendekati nilai ideal yaitu 0 artinya dosis yang diterima oleh target memiliki keseragaman. Nilai CI yang diperoleh pada variasi 5,7 dan 9 berturut−turut 0,9955; 0,9965; dan 0,9968. Nilai CI ketiga lapangan mendekati ideal yaitu 1. Hal ini menandakan distribusi dosis memiliki kesesuaian dengan bentuk target. Diskrepansi dosis pada PTV sesuai dengan batas toleransi yang ditetapkan pada TRS 398. Diskrepansi dosis pada organ at risk memiliki nilai lebih dari 5%, hal ini tidak sesuai dengan batas toleransi yang ditetapkan TRS 398. Berdasarkan analisis statistik , tidak ada perbedaan yang signifikan antara hasil pengukuran dan perencanaan yang artinya nilai diskrepansi dosis masih bisa diterima.
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Radiotherapy planning for oropharyngeal cancer has been carried out using the 6MV Intensity Modulated Radiotherapy (IMRT) technique. This study aims to evaluate the target absorption dose and organ at risk, evaluate the Homogeneity Index (HI) and Conformity Index (CI) values, evaluate the dose difference from the Treatment planning System (TPS) and the measurement results using EBT3 film. IMRT planning was carried out using Eclipse software on a 3D Printed Head−Neck Phantom with a dose of 200 cGy 30 fractions and the number of fields were 5,7, and 9. The target absorption dose of 9 fields had a dose that covered the PTV area more than 7 fields and 5 fields. The absorbed dose in organs at risk using 5 fields received a higher dose than other fields. The accepted HI value in variations 5, 7 and 9 courts are 0.0697; 0.0753; and 0.0705 respectively. The HI value is close to the ideal value, which is 0 which means that the dose received by the target has uniformity. The CI values obtained at variations of 5.7 and 9 are 0.9955; 0.9965; and 0.9968, respectively. The CI values of the three fields are close to ideal, namely 1. This indicates that the dose distribution is in accordance with the target shape. The dose discrepancy at PTV is in accordance with the tolerance limit set in TRS 398. The dose discrepancy in some organs at risk has a value of more than 5%, this is not in accordance with the tolerance limit set by TRS 398. Based on statistical analysis, there is no significant difference between the measurement and planning results, which means that the dose discrepancy value is still acceptable.

Item Type:	Thesis (Other)
Uncontrolled Keywords:	CI, HI, IMRT, Jumlah Lapangan, Kanker Orofaring, Radioterapi, Number of Fields, Oropharyngeal Cancer, Radiotherapy
Subjects:	Q Science > QC Physics Q Science > QR Microbiology > QR 201.T84 Tumors. Cancer
Divisions:	Faculty of Science and Data Analytics (SCIENTICS) > Physics > 45201-(S1) Undergraduate Thesis
Depositing User:	Mr. Marsudiyana -
Date Deposited:	16 Dec 2025 12:24
Last Modified:	16 Dec 2025 12:24
URI:	http://repository.its.ac.id/id/eprint/129012

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