Desain Pabrik Isosorbida Berbasis Glukosa Dengan Metode Hidrogenasi-Dehidrasi Katalitik

Ananta, Chika Galuh Putri and Maharani, Nashita Yustya Erlina (2026) Desain Pabrik Isosorbida Berbasis Glukosa Dengan Metode Hidrogenasi-Dehidrasi Katalitik. Other thesis, Institut Teknologi Sepuluh Nopember.

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Abstract

Isosorbida (C6H10O4) merupakan senyawa diol siklik berbasis biomassa yang dimanfaatkan sebagai intermediate untuk berbagai produk bernilai tambah, seperti monomer polimer dan turunan nitrat untuk obat kardiovaskular. Isosorbida diproduksi melalui hidrogenasi katalitik sirup glukosa menjadi sorbitol menggunakan gas H2 dan katalis Raney Nickel dalam stirred tank reactor (STR), kemudian didehidrasi menjadi isosorbida menggunakan katalis Amberlyst-36 pada reaktor tangki berpengaduk. Produk hasil kristalisasi dipisahkan menggunakan centrifuge dan dikeringkan dengan vacuum tray dryer hingga memenuhi spesifikasi kadar air. Pabrik direncanakan berlokasi di Kecamatan Ketapang, Kabupaten Lampung Selatan, Provinsi Lampung, dengan mempertimbangkan ketersediaan bahan baku, kemudahan distribusi, dan utilitas. Berdasarkan analisis ekonomi, pabrik membutuhkan total investasi sebesar Rp21.449.294.216.506,70 dengan biaya produksi tahunan Rp17.195.336.400.305,50 dan penjualan Rp21.567.000.000.000,00 per tahun. Evaluasi ekonomi menunjukkan nilai Internal Rate of Return (IRR) sebesar 30,28%, Payout Time (POT) selama 3,07 tahun, dan Break Even Point (BEP) sebesar 39,59%, sehingga pabrik dinilai layak untuk direalisasikan.
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Isosorbide (C6H10O4) is a biomass-based cyclic diol widely used as an intermediate for various value-added products, including polymer monomers and nitrate derivatives for cardiovascular pharmaceuticals. Isosorbide is produced through two main stages: catalytic hydrogenation of glucose syrup into sorbitol using hydrogen gas and a Raney nickel catalyst in a pressurized stirred tank reactor (STR), followed by the dehydration of sorbitol into isosorbide using an Amberlyst-36 catalyst in a stirred tank reactor. The crystallized product is separated using a centrifuge and subsequently dried in a vacuum tray dryer to achieve the required moisture content specification. The proposed isosorbide plant is located in Ketapang District, South Lampung Regency, Lampung Province, considering the availability of raw materials, ease of product distribution, and supporting utilities. Based on the economic evaluation, the plant requires a total investment of IDR 21,449,294,216,506.70, with an annual production cost of IDR 17,195,336,400,305.50 and annual sales revenue of IDR 21,567,000,000,000.00. The economic analysis indicates an Internal Rate of Return (IRR) of 30.28%, a Payout Time (POT) of 3.07 years, and a Break Even Point (BEP) of 39.59%, demonstrating that the proposed isosorbide plant is economically feasible.

Item Type:	Thesis (Other)
Uncontrolled Keywords:	Dehidrasi, Glukosa, Hidrogenasi, Isosorbida, Katalis Dehydration, Glucose, Hydrogenation, Isosorbide, Catalyst
Subjects:	T Technology > TP Chemical technology > TP155.5 Chemical plants--Design and construction
Divisions:	Faculty of Industrial Technology and Systems Engineering (INDSYS) > Chemical Engineering > 24201-(S1) Undergraduate Thesis
Depositing User:	Chika Galuh Putri Ananta
Date Deposited:	27 Jul 2026 01:24
Last Modified:	27 Jul 2026 01:24
URI:	http://repository.its.ac.id/id/eprint/137600

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