Pemodelan Matematika Hemodinamika Pada Kasus Branch Retinal Vein Occlusion (BRVO) Dengan Pengaruh Stenosis Asimetris

Febrianti, Erwin (2026) Pemodelan Matematika Hemodinamika Pada Kasus Branch Retinal Vein Occlusion (BRVO) Dengan Pengaruh Stenosis Asimetris. Other thesis, Institut Teknologi Sepuluh Nopember.

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Abstract

Branch Retinal Vein Occlusion (BRVO) merupakan gangguan aliran darah pada cabang vena retina yang dapat menyebabkan penurunan fungsi penglihatan akibat adanya hambatan atau penyempitan pada pembuluh darah. Penelitian ini menganalisis pengaruh variasi bentuk geometri stenosis asimetris, yaitu Bell-Gaussian, Bell-Elliptical, dan Gaussian-Elliptical, terhadap karakteristik aliran darah berupa kecepatan, tekanan, dan temperatur. Aliran darah diasumsikan sebagai fluida non-Newtonian Casson, incompressible, dan unsteady. Model matematika dikembangkan berdasarkan persamaan konservasi massa, momentum, dan energi, kemudian didiskritisasi menggunakan Finite Volume Method (FVM) dengan algoritma SIMPLER. Simulasi dilakukan menggunakan MATLAB dan ANSYS dengan variasi ketebalan stenosis 45%, 60%, dan 75%. Hasil simulasi menunjukkan bahwa peningkatan ketebalan stenosis menyebabkan kenaikan kecepatan aliran darah, penurunan tekanan setelah melewati daerah stenosis, serta peningkatan temperatur di sekitar throat. Pada stenosis 75%, model Gaussian-Elliptical memberikan pengaruh paling signifikan dengan kecepatan maksimum sebesar 6,951, tekanan maksimum sebelum melewati stenosis sebesar 1027, serta temperatur maksimum sekitar 1,0000004. Hasil MATLAB dan ANSYS Fluent menunjukkan pola distribusi yang konsisten, sehingga model yang dikembangkan dapat digunakan untuk menggambarkan karakteristik hemodinamika pada kasus BRVO dengan stenosis asimetris.
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Branch Retinal Vein Occlusion (BRVO) is a blood flow disorder in the branch retinal vein that can lead to visual impairment due to obstruction or narrowing of the blood vessels. This study analyzes the effect of asymmetric stenosis geometry variations, namely Bell-Gaussian, Bell Elliptical, and Gaussian-Elliptical, on blood flow characteristics, including velocity, pressure, and temperature. Blood flow is modeled as a non-Newtonian Casson fluid with incompressible and unsteady properties. The mathematical model is developed based on the conservation equations of mass, momentum, and energy, and is discretized using the Finite Volume Method (FVM) with the SIMPLER algorithm. Simulations are conducted using MATLAB and ANSYS Fluent with stenosis thickness variations of 45%, 60%, and 75%. The simulation results show that increasing stenosis thickness leads to an increase in blood flow velocity, a decrease in pressure after passing through the stenotic region, and a rise in temperature around the throat. At 75% stenosis, the Gaussian-Elliptical model produces the most significant effect, with a maximum velocity of 6.951, a maximum pressure before the stenosis of 1027, and a maximum temperature of approximately 1.0000004. The MATLAB and ANSYS Fluent results show consistent distribution patterns. Therefore, the developed model can be used to describe the hemodynamic characteristics of BRVO cases with asymmetric stenosis.

Item Type:	Thesis (Other)
Uncontrolled Keywords:	Branch Retinal Vein Occlusion (BRVO), Finite Volume Method, Stenosis Asimetris, SIMPLER. Branch Retinal Vein Occlusion (BRVO), Finite Volume Method, Asymmetric Stenosis, SIMPLER
Subjects:	Q Science Q Science > QA Mathematics Q Science > QA Mathematics > QA911 Fluid dynamics. Hydrodynamics
Divisions:	Faculty of Science and Data Analytics (SCIENTICS) > Mathematics > 44201-(S1) Undergraduate Thesis
Depositing User:	Erwin Febrianti
Date Deposited:	29 Jul 2026 04:07
Last Modified:	29 Jul 2026 04:07
URI:	http://repository.its.ac.id/id/eprint/139049

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