Esterifikasi asam 4-metilsinamat dengan metoda shiina

Pasha, Maulidina (2022) Esterifikasi asam 4-metilsinamat dengan metoda shiina. Other thesis, Institut Teknologi Sepuluh Nopember.

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Abstract

Turunan asam sinamat banyak digunakan dalam kosmetik sebagai wewangian, tabir surya, perawatan kulit (tonik, pencerah kulit, anti-aging), hair conditioning, antioksidan, dan antimikroba. Penelitian yang telah dilakukan berhasil mendapatkan turunan asam 4-metilsinamat baru berupa fenetil (E)-3-(4-tolil)akrilat dan 4-metoksifenetil (E)-3-(4-tolil)akrilat. Reaksi esterifikasi Shiina yang melibatkan asam 4-metilsinamat dan 2-feniletanol diperoleh fenetil (E)-3-(4-tolil)akrilat dengan rendemen 62%, sedangkan reaksi yang melibatkan asam 4-metilsinamat dengan 4-metoksifenetil alkohol diperoleh 4-metoksifenetil (E)-3-(4-tolil)akrilat dengan rendemen 63%. Struktur kedua senyawa baru ditetapkan dengan menggunakan spektra yang diperoleh dengan spektrometer NMR (¹H, ¹³C), spektrometer massa resolusi tinggi (HRESIMS), spektrofotometer FTIR, dan spektrofotometer UV-Vis. Spektrum UV-Vis kedua senyawa masing-masing memberikan λmaks 286 dan 284 nm, sehingga memungkinkan keduanya digunakan sebagai tabir surya maupun senyawa pewangi.
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Cinnamic acid derivatives are widely used in cosmetics as fragrances, sunscreens, skincare (tonic, skin lightening, anti-aging), hair conditioning, antioxidants, and antimicrobials. The research that has succeeded in obtaining new 4-methylcinnamic acid derivatives in the form of phenethyl (E)-3-(4-tolil)acrylate and 4-methoxyphenetil (E)-3-(4-toleryl)acrylate. The esterification reaction of Shiina involving 4-methylcinnamic acid and 2-phenylethanol obtained phenethyl (E)-3-(4-tolil)acrylic with a yield of 62%, while a reaction involving 4- methylethautic acid with 4-methoxyreneline alcohol obtained 4-methoxyphenetil (E)-3-(4- toleryl)acrylate with a yield of 63%. The structure of the two new compounds was established using spectra obtained with NMR spectrometers (1H, 13C), high-resolution mass spectrometers (HRESIMS), FTIR spectrophotometers, and UV-Vis spectrophotometers. The UV-Vis spectrum of the two compounds provides λmax 286 and 284 nm, respectively, allowing both to be used as sunscreens and fragrance compounds.

Item Type:	Thesis (Other)
Additional Information:	RSKi 541.39 Pas e-1
Uncontrolled Keywords:	2-feniletanol, 4-metoksifenetil alkohol, Asam 4-metilsinamat, Metoda Shiina. , 2-phenylethanol, 4-methylcinnamic acid, 4-methoxyphenethyl alcohol, Shiina Method.
Subjects:	Q Science > QD Chemistry > QD305.A2 O73 Esterification
Divisions:	Faculty of Mathematics and Science > Chemistry > 47201-(S1) Undergraduate Thesis
Depositing User:	magang .
Date Deposited:	30 Sep 2026 04:18
Last Modified:	30 Oct 2026 00:39
URI:	http://repository.its.ac.id/id/eprint/145079

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