Muthiah, Faizatul (2017) Tiga Santon Terprenilasi dari Akar Garcinia tetrandra Pierre. Undergraduate thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Garcinia tetrandra Pierre merupakan salah satu tumbuhan endemik di Indonesia yang telah dikenal sebagai sumber senyawa santon. Pada penelitian ini, tiga senyawa santon terprenilasi, yaitu parvifolisanton C (1), maklurasanton (2) dan 9-hidroksikalabasanton (3), telah berhasil diisolasi dari akar G.tetrandra Pierre yang berasal dari Taman Nasional Meru Betiri Jember, Jawa Timur. Proses ekstraksi menggunakan pelarut metilena klorida dan difraksinasi menggunakan metode kromatografi cair vakum, kromatografi kolom gravitasi, kromatografi gel filtrasi dan sentrifugal kromatografi lapis tipis. Proses pemurnian senyawa dilakukan dengan metode rekristalisasi. Penentuan struktur senyawa ditentukan berdasarkan analisis data spektroskopi UV-Vis, IR, 1H dan 13C-NMR.
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Garcinia tetrandra Pierre is one of endemic flora in Indonesia that has been known as the source of xanthones. In this research, three prenilated xanthones, named Parvifolisanton C (1), macluraxanthone (2) dan 9-hydroxycalabaxanthone (3), were isolated from root of G.tetrandra Pierre which came from Taman Nasional Meru Betiri Jember, East Java. That three compounds were extracted with metilene chloride, separated by vacuum liquid chromatography, column gravity chromatography, gel filtration chromatography and centrifugally accelerated thin layer chromatography, and also purificated by recrystalitation method. Their structure were determined by spectroscopic methods with UV, IR, 1H and 13C-NMR. Three compounds that have been found can complete the mapping compunds of G.tetrandra Pierre.
| Item Type: | Thesis (Undergraduate) |
|---|---|
| Additional Information: | RSKi 543.8 Mut t-1 |
| Uncontrolled Keywords: | Garcinia tetrandra Pierre, Guttiferae, Santon terprenilasi. |
| Subjects: | Q Science Q Science > QD Chemistry |
| Divisions: | Faculty of Mathematics and Science > Chemistry > 47201-(S1) Undergraduate Thesis |
| Depositing User: | Faizatul Muthiah . |
| Date Deposited: | 20 Dec 2017 07:27 |
| Last Modified: | 06 Mar 2019 02:26 |
| URI: | http://repository.its.ac.id/id/eprint/47417 |
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