Pengukuran Kadar Kolesterol Pada Jaringan Kulit Tiruan (Phantom) Menggunakan Teknik Diffuse Reflectance Spectroscopy

Putri, Firda Julianita Pradina (2017) Pengukuran Kadar Kolesterol Pada Jaringan Kulit Tiruan (Phantom) Menggunakan Teknik Diffuse Reflectance Spectroscopy. Undergraduate thesis, Institut Teknologi Sepuluh Nopember.

[img]
Preview
Text
2415105009-Undergraduate_Theses.pdf - Published Version

Download (2MB) | Preview

Abstract

Kadar kolesterol darah yang tinggi akan menyebabkan terjadinya penyempitan pembuluh darah (aterosklerosis). Aterosklerosis dapat memicu berbagai penyakit serius seperti penyakit jantung, stroke, dan bahkan dapat menyebabkan kematian. Pendeteksian peningkatan kolesterol secara lebih dini sangat dibutuhkan untuk mencegah terjadinya aterosklerosis. Salah satu metode berbasis optik untuk pengukuran kadar kolesterol secara non-invasif atau minimally invasive adalah Diffuse Reflectance Spectroscopy (DRS), yang memanfaatkan terjadinya pantulan difus pada permukaan objek uji. Tujuan penelitian ini adalah membangun dan menguji teknik pengukuran kadar kolestrol dengan menggunakan teknik DRS. Pengukuran dilakukan dalam phantom cairan (yang merepresentasikan nilai-nilai parameter optis dari jaringan kulit: yaitu koefisien serapan dan koefisien hamburan). Phantom ini dibuat dari campuran intralipid dengan penambahan beberapa nilai konsentrasi larutan kolesterol, yang dibuat dengan melarutkan bubuk kolesterol murni dengan pelarut ethanol. Berdasarkan pengujian yang telah dilakukan, korelasi yang baik antara koefisien absorpsi phantom dan kadar kolesterol telah didapatkan untuk pengukuran kadar kolesterol pada phantom menggunakan Diffuse reflektance spectroscopy pada rentang 2,752 cm-1 sampai 3,57 cm-1 dengan nilai akurasi yang dihasilkan adalah 90,3%, dan tingkat kepresisian sebesar 0,96%. ================================================================================================== High cholesterol in blood may lead to vascular constriction (atherosclerosis). Atherosclerosis can stimulate other diseases, such as coronary vascular disease (CVD), stroke, and can even cause death. Early detection of cholesterol rising level is needed to prevent atherosclerosis. One of the optical-based methods for non-invasive or minimally invasive cholesterol measurement is Diffuse Reflectance Spectroscopy (DRS), which utilizes the occurrence of diffuse reflections on the surface of the test object. The purpose of this research is to build and test the technique of measuring cholesterol level using DRS technique. Measurements are made in liquid phantom (which represents the optical parameter values of the skin tissue: i.e. the absorption coefficient and the scattering coefficient). This phantom is made from an intralipid mixture by varying several concentration value of of cholesterol solution, which is prepared by dissolving pure cholesterol powder with ethanol solvent. Based on the tests done, a good correlation between phantom absorption coefficient and cholesterol levels has been obtained for measurement of cholesterol levels in phantom using Diffuse reflectance spectroscopy at a range of 2.752 cm-1 to 3.57 cm-1 with accuracy of 93%, and the precision of 0,96% .

Item Type: Thesis (Undergraduate)
Additional Information: RSE 621.361 Put p-1
Uncontrolled Keywords: Diffuse Reflectance Spectroscopy, cholesterol concentration, noninvasive measurement technique, liquid phantom
Subjects: R Medicine > RZ Other systems of medicine
T Technology > TK Electrical engineering. Electronics Nuclear engineering > TK7872 Electromagnetic Devices
Divisions: Faculty of Industrial Technology > Physics Engineering > (S1) Undergraduate Theses
Depositing User: Firda Julianita Pradina Putri
Date Deposited: 02 Jan 2018 04:23
Last Modified: 06 Mar 2019 02:28
URI: http://repository.its.ac.id/id/eprint/47486

Actions (login required)

View Item View Item