Hidayati, Mutia Devi (2015) Pemisahan Dan Identifikasi Antioksidan Dan Inhibitor α-Glukosidase Dari Daun Salam. Undergraduate thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Daun salam merupakan obat herbal yang tumbuh di Asia Tenggara. Pada
penelitian ini, 3,4,5-trihidroksi-asam benzoat dan senyawa benzofuran telah diisolasi
dari ekstrak metanol S. polyanthum dengan metode ekstraksi, partisi dan
kromatografi. Struktur kimia telah ditentukan menggunakan data spektroskopi 1HNMR
dan 13C-NMR. Uji aktivitas antidiabetes dilakukan menggunakan
α-glukosidase menunjukkan bahwa asam galat dapat dikatakan aktif sebagai
antidiabetes. Aktivitas asam galat sebagai antidiabetes berkaitan erat dengan sifatnya
sebagai antioksidan. Asam galat menunjukkan penghambatan antioksidan melalui
DPPH (2,2-diphenyl-2-picrylhydrazyl hydrate) dan ABTS (2,2’-azinobis (3-ethyl
benzothiazoline-6-sulfonic acid) drazyl hydrate)
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Syzygium polyanthum is a herbal medicine which is grown in South East
Asia. In this study, 3,4,5-trihydroxy-benzoic acid and benzofuran compound
puranol were isolated from methanol extract of S. polyanthum by extraction,
partition and chromatography methods. The chemical structures were determined
by using 1H-NMR and 13C-NMR spectroscopic data. Antidiabetic activity was
done with α-glucosidase showed that gallic acid could be active as antidiabetic.
Activity of gallic acid as antidiabetic closely related to its antioxidant activity.
Gallic acid showed antioxidant inhibition on DPPH (2,2-diphenyl-2-
picrylhydrazyl hydrate) and ABTS (2,2’-azinobis (3-ethyl benzothiazoline-6-
sulfonic acid)
| Item Type: | Thesis (Undergraduate) |
|---|---|
| Additional Information: | RTKi 660.284 2 Hid p |
| Uncontrolled Keywords: | α-glukosidase, DPPH, ABTS. |
| Subjects: | T Technology > TP Chemical technology > TP156 Crystallization. Extraction (Chemistry). Fermentation. Distillation. Emulsions. |
| Divisions: | Faculty of Mathematics and Science > Chemistry > 47101-(S2) Master Thesis |
| Depositing User: | Mr. Tondo Indra Nyata |
| Date Deposited: | 21 Mar 2018 04:26 |
| Last Modified: | 24 Aug 2018 03:10 |
| URI: | http://repository.its.ac.id/id/eprint/51596 |
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