Ariyani, Debora (2015) Isolasi Senyawa Asam lemak, Terpenoid dan Bioaktivitas Antioksidan dari Tumbuhan Kacang Kayu (Cajanus cajan (L) Millsp) dari Pulau Poteran - Madura. Masters thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Dua senyawa asam lemak dan satu senyawa terpenoid telah berhasil diisolasi dari ekstrak metanol tumbuhan kacang kayu (Cajanus cajan (L) Millsp) yang terdapat di Pulau Poteran-Madura yaitu 2-Hidroksi Asam icosanat dan 3- (4’,8’,12’- trimetiltridesil) sikloheksena-1-ol. Pada penelitian ini, pemisahan senyawa dilakukan dengan ekstraksi secara maserasi dan kombinasi teknik kromatografi. Penentuan struktur dilakukan menggunakan data spektroskopi UV, IR, 1H-NMR dan 13C-NMR dan dengan perbandingan data yang telah dilaporkan sebelumnya. Berdasarkan pengujian antioksidan menggunakan radikal DPPH (2,2-difenil-1-pikrilhidrazil) yang telah dilakukan diketahui bahwa 2-Hidroksi Asam icosanat bersifat tidak aktif dan 3- (4’,8’,12’- trimetiltridesil) sikloheksena-
1-ol bersifat lemah dengan nilai IC50 271,53 μg/mL.
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Fatty acid derivatives and terpenoid had been isolated from methanol extract of kacang kayu (Cajanus cajan (L) Millsp) from Poteran-MaduraIsland, namely
2-hydroxy icosanoic acid, and 3-(4’,8’,12’- trimethyltridecyl) cyclohexena-1-ol. Isolation of compounds were achieved by extraction (maceration) and combination of chromatographic technique. The structure of the compound were determined basis on UV, IR , 1H-NMR and 13C-NMR spectra and by c omparing with the previously reported data. These compounds were evaluated for its in vitro antioxidant activity using 2,2 - diphenyl - 1 – picrylhydrazyl (DPPH) radical- scavenging have 2-hydroxy icosanoic acid not active and 3-(4’,8’,12’-
trimethyltridecyl) cyclohexena-1-ol IC50 271,53 μg/mL.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | RTKi 547.71 Ari i |
| Uncontrolled Keywords: | Cajanus cajan (L) Millsp, asam lemak, terpenoid, antioksidan, 2,2-difenil-1-pikrilhidrazil, fatty acid, 2,2-diphenyl-1–picrylhydrazyl (DPPH) |
| Subjects: | Q Science > QD Chemistry R Medicine > R Medicine (General) |
| Divisions: | Faculty of Mathematics and Science > Chemistry > 47101-(S2) Master Thesis |
| Depositing User: | Eny Widiastuti - |
| Date Deposited: | 08 May 2018 08:58 |
| Last Modified: | 24 Aug 2018 02:03 |
| URI: | http://repository.its.ac.id/id/eprint/51852 |
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