Habibah, Tutut Ummul (2014) Alternatif baru penembangan material semen tulang/bone cement (CH-[CH-HA]- CaCO2-MMA) hasil daur ulang limbah organik. Undergraduate thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Pengembangan semen tulang yang bersifat lebih adaptif
terhadap metabolisme tubuh merupakan hal yang sangat penting
dalam dunia orthopedic. Penggunaan bahan dasar semen tulang
yang bersifat biodegradable seperti chitosan, karbonathidroksiapatit,
dan karbonat [C-(C-HA)-CaCO3] yang diproduksi
dari limbah organik serta MMA sebagai resin merupakan suatu
langkah agar proses osteeokonduksi dan osteointegrasi dapat
berjalan lebih efisien. Hasil analisa menunjukkan bahwa ketiga
sample C2H1K3L, C2H24K24L dan C2H3K1L memiliki nilai
zona halo inhibiton lebih tinggi dari standar pada umumya (1mm)
dengan panjang masing-masing sebesar 7.7mm, 14.2mm dan
7.5mm, selain itu ketiga kandidat memiliki nilai
konduktivitas thermal yang aman bagi tubuh sebesar 0.30
mW/oC, 0.25 mW/oC, 0.30 mW/oC pada temperatur 37OC
dan 0.44 mW/oC, 0.49 mW/oC, 0.40 mW/oC pada
temperatur 45oC. Penambahan rasio CaCO3 akan menyebabkan
semen tulang memiliki nilai kekerasan yang sesuai dengan
kekerasan tulang manusia sebesar 36.84 HV (C2H1K3L ) dan
terbentuknya pori interkoneksi yang akan mendukung terjadinya
pertumbuhan jaringan tulang secara lebih efisien. =========== Nowadays, development in more adaptable bone
cement in human body reaches the important place in
orthopedic field. The usage of more biodegradable materials
such as chitosan, carbonated-hydroxyapatite, calcium
carbonate which was produced from bio waste materials and
MMA as a resin is the most potential way to lead
osteointegration and osteoconduction to occurs, which could
make healing and recovery process more efficient. The
results depicted that the three samples C2H1K3L,
C2H24K24L and C2H3K1L had greater of halo inhibiton
zone referred than particular standart (1mm) for 7.7mm,
14.2mm, and 7.5 mm respecively. The three candidats have
lower thermal conductivity than human bone for 0.30 mW/oC,
0.25 mW/oC, 0.30 mW/oC respectively at 37OC and 0.44
mW/oC, 0.49 mW/oC, 0.40 mW/oC at 45oC. Interconnected
porous and successfully mimicking bone hardness by
C2H1K3L (36.84 HV) were produced by increasing ratio of
CaCO3 in composition. Generally, all the samples were
promising candidates as a bone cement because of their ability
to provide properties which could support for bone tissue
regeneration.
| Item Type: | Thesis (Undergraduate) |
|---|---|
| Additional Information: | RSMt 620.135 Hab a |
| Uncontrolled Keywords: | chitosan, karbonat-hidroksipatit, karbonat, MMA, semen tulang, bone cement, chitosan, carbonatedhidroxyapatite, carbonate |
| Subjects: | H Social Sciences > HD Industries. Land use. Labor > HD9622 Cement. Concrete. Cement and concrete additives |
| Divisions: | Faculty of Industrial Technology > Material & Metallurgical Engineering > 28201-(S1) Undergraduate Thesis |
| Depositing User: | - Davi Wah |
| Date Deposited: | 26 Mar 2019 07:59 |
| Last Modified: | 26 Mar 2019 07:59 |
| URI: | http://repository.its.ac.id/id/eprint/62591 |
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