Alternatif baru penembangan material semen tulang/bone cement (CH-[CH-HA]- CaCO2-MMA) hasil daur ulang limbah organik

Habibah, Tutut Ummul (2014) Alternatif baru penembangan material semen tulang/bone cement (CH-[CH-HA]- CaCO2-MMA) hasil daur ulang limbah organik. Undergraduate thesis, Institut Teknologi Sepuluh Nopember.

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Abstract

Pengembangan semen tulang yang bersifat lebih adaptif terhadap metabolisme tubuh merupakan hal yang sangat penting dalam dunia orthopedic. Penggunaan bahan dasar semen tulang yang bersifat biodegradable seperti chitosan, karbonathidroksiapatit, dan karbonat [C-(C-HA)-CaCO3] yang diproduksi dari limbah organik serta MMA sebagai resin merupakan suatu langkah agar proses osteeokonduksi dan osteointegrasi dapat berjalan lebih efisien. Hasil analisa menunjukkan bahwa ketiga sample C2H1K3L, C2H24K24L dan C2H3K1L memiliki nilai zona halo inhibiton lebih tinggi dari standar pada umumya (1mm) dengan panjang masing-masing sebesar 7.7mm, 14.2mm dan 7.5mm, selain itu ketiga kandidat memiliki nilai konduktivitas thermal yang aman bagi tubuh sebesar 0.30 mW/oC, 0.25 mW/oC, 0.30 mW/oC pada temperatur 37OC dan 0.44 mW/oC, 0.49 mW/oC, 0.40 mW/oC pada temperatur 45oC. Penambahan rasio CaCO3 akan menyebabkan semen tulang memiliki nilai kekerasan yang sesuai dengan kekerasan tulang manusia sebesar 36.84 HV (C2H1K3L ) dan terbentuknya pori interkoneksi yang akan mendukung terjadinya pertumbuhan jaringan tulang secara lebih efisien. =========== Nowadays, development in more adaptable bone cement in human body reaches the important place in orthopedic field. The usage of more biodegradable materials such as chitosan, carbonated-hydroxyapatite, calcium carbonate which was produced from bio waste materials and MMA as a resin is the most potential way to lead osteointegration and osteoconduction to occurs, which could make healing and recovery process more efficient. The results depicted that the three samples C2H1K3L, C2H24K24L and C2H3K1L had greater of halo inhibiton zone referred than particular standart (1mm) for 7.7mm, 14.2mm, and 7.5 mm respecively. The three candidats have lower thermal conductivity than human bone for 0.30 mW/oC, 0.25 mW/oC, 0.30 mW/oC respectively at 37OC and 0.44 mW/oC, 0.49 mW/oC, 0.40 mW/oC at 45oC. Interconnected porous and successfully mimicking bone hardness by C2H1K3L (36.84 HV) were produced by increasing ratio of CaCO3 in composition. Generally, all the samples were promising candidates as a bone cement because of their ability to provide properties which could support for bone tissue regeneration.

Item Type: Thesis (Undergraduate)
Additional Information: RSMt 620.135 Hab a
Uncontrolled Keywords: chitosan, karbonat-hidroksipatit, karbonat, MMA, semen tulang, bone cement, chitosan, carbonatedhidroxyapatite, carbonate
Subjects: H Social Sciences > HD Industries. Land use. Labor > HD9622 Cement. Concrete
Divisions: Faculty of Industrial Technology > Material & Metallurgical Engineering > (S1) Undergraduate Theses
Depositing User: - Davi Wah
Date Deposited: 26 Mar 2019 07:59
Last Modified: 26 Mar 2019 07:59
URI: http://repository.its.ac.id/id/eprint/62591

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