Ikrari, Karaben Ikhtiyana (2015) Lipid makroalga ceratodictyon spongiosum : sebagai biomarka dan senyawa bioaktif. Undergraduate thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Makroalga Ceratodictyon spongiosum merupakan jenis alga
filum Rhodophyta yang banyak ditemukan di perairan tropis pulau
Talango, Sumenep, Jawa Timur. Kondisi ekosistem wilayah
tersebut memungkinkan organisme makroalga menghasilkan
berbagai bahan organik yang bersifat aktif sebagai agen
pertahanan. Bahan organik tersebut merupakan senyawa khas
untuk organisme makroalga yang dapat menjadi marka
bioaktivitasnya. Ekstrak makroalga Ceratodictyon spongiosum
berhasil dipisahkan dari fraksi n-heksana ekstrak metanol
menggunakan kromatografi cair – spektroskopi massa.
Identifikasi lipid dominan menghasilkan beberapa fosfolipid dan
glikolipid serta satu jenis PUFA. Fraksi n-heksana ekstrak
metanol diketahui aktif terhadap bakteri gram negatif E. coli dan
bakteri gram positif S. aureus. Senyawa-senyawa isolat dapat
digunakan sebagai marka makroalga Ceratodictyon spongiosum
serta bioaktivitasnya pada perairan tropis.
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Macroalgae Ceratodictyon spongiosum represent of phylum
Rhodophyta which is highly found in tropical ocean Talango
island, Sumenep, Jawa Timur. The ecosystem of those area enable
the macroalgae producing various biologically active organic
substances. The organic substances characterize the typical
compound for those macroalgae which can be biologically active
markers. The result compounds were extracted from n-hexane
fraction of methanol extract by liquid chromatography – mass
spectrometry. Major lipid of macroalgae Ceratodictyon
spongiosum obtained as phospholipid, glycolipid and PUFA. Nhexane
fraction of methanol extract was evaluated for
antibacterial activity against gram-negative strain E. coli and
gram-positive strain S. aureus. The result compounds are useful as
biomarker of macroalgae Ceratodictyon spongiosum and its
antibacterial activity in those area.
| Item Type: | Thesis (Undergraduate) |
|---|---|
| Additional Information: | RSKi 572.57 Ikr l |
| Uncontrolled Keywords: | Ceratodictyon spongiosum; biomarka; bioaktif; lipid |
| Subjects: | Q Science > QD Chemistry > QD471 Chemical compounds - Structure and formulas |
| Divisions: | Faculty of Mathematics and Science > Chemistry > 47201-(S1) Undergraduate Thesis |
| Depositing User: | - Taufiq Rahmanu |
| Date Deposited: | 25 Jun 2019 04:24 |
| Last Modified: | 09 Jan 2020 02:45 |
| URI: | http://repository.its.ac.id/id/eprint/63240 |
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