Bakhtiar, Muhammad (2019) Pengaruh Katalis Seng Asetat Terhadap Berat Molekul, Biodegradasi, dan Water Absorption pada Poli(Asam Laktat) Hasil Sintesis Metode Ring-Opening Polimerization Laktida dari Asam Laktat. Other thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Poli(asam laktat) (PLA) merupakan senyawa keluarga poliester alifatik yang berasal dari sintesis asam α – hidroksi. PLA memiliki sifat biodegradabel dan biokompatibel yang baik sehingga dapat diaplikasikan sebagai implant, benang operasi, dan drug delivery. PLA diperoleh dengan cara sintesis asam laktat menggunakan metode ring – opening polymerization (ROP) laktida. Proses polimerisasi PLA dari asam laktat menggunakan katalis seng asetat. Salah satu faktor yang berpengaruh pada sintesis PLA adalah konsentrasi katalis. Penambahan katalis meningkatkan laju reaksi sehingga mempercepat pembentukan PLA. Sintesis PLA dari asam laktat dilakukan melalui tiga tahap yaitu prepolimerisasi, depolimerisasi, dan polimerisasi. Prepolimerisasi asam laktat menghasilkan oligomer PLA sedangkan depolimerisasi menghasilkan laktida. ROP laktida dilakukan menggunakan katalis seng asetat dengan variasi konsentrasi yaitu 0; 0,2; 0,4; 0,6; dan 0,8%wt dengan temperatur reaksi 150oC selama lima jam dengan tekanan -2 bar. Berdasarkan hasil FTIR, PLA sintesis memiliki kemiripan dengan PLA standar. Peak pada wavenumber 3486 cm-1 merupakan gugus fungsi –OH stretch, peak pada wavenumber 1741 cm-1 menunjukkan gugus fungsi –C=O stretch, dan peak pada wavenumber 1124 dan 1085 cm-1 menunjukkan gugus fungsi –C-O- stretch. Penambahan katalis seng asetat pada ROP laktida meningkatkan berat molekul PLA, menurunkan biodegradasi, dan menurunkan persentase water absorption, namun penambahan katalis ketingkat yang lebih tinggi menyebabkan berat molekul berkurang sedangkan biodegradasi dan persentase water absorption meningkat. Berat molekul, persentase weight loss, dan water absorption optimum diperoleh pada penambahan katalis seng asetat (0,4%wt) sebesar 18.434 g/mol, 61,75%, dan 8,25%.
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Poly(lactic acid) (PLA) is an aliphatic polyester family compound derived from the synthesis of α-hydroxy acids. PLA has good biodegradable and biocompatible properties so that it can be applied as an implant, surgical thread, and drug delivery. PLA is obtained by synthesis of lactic acid using the lactide ring-opening polymerization (ROP) method. The PLA polymerization process from lactic acid was used zinc acetate catalyst. The factors that influence the synthesis of PLA is the concentration of the catalyst. The addition of the catalyst increases the rate of reaction thereby accelerating the formation of PLA. The synthesis of PLA from lactic acid was carried out through the pre-polymerization, depolymerization and polymerization stages. Pre-polymerization of lactic acid produces PLA oligomers and depolymerization of PLA oligomers produces lactide. ROP of Lactide was carried out using zinc acetate catalyst with a concentration of 0; 0.2; 0.4; 0.6; and 0.8%wt and a reaction temperature of 150oC for five hours with a pressure of -2 bar. Based on the results of FTIR, synthesized PLA has similarities with standard PLA. Peak on wavenumber 3486 cm-1 shows –OH stretch, peak at wavenumber 1741 cm-1 shows –C=O stretch, and peak on wavenumber 1124 and 1085 cm-1 shows –C-O-stretch. The addition of zinc acetate catalyst on ROP lactide increases the molecular weight of PLA, decreases degradation, and decreases the percentage of water absorption, but the addition of a higher level catalyst causes reduced molecular weight while degradation and water absorption percentage are increased. The optimum molecular weight, weight loss, and water absorption percentage obtained by adding zinc acetate catalyst (0.4% wt) was 18,434 g / mol, 61.75%, and 8.25%.
| Item Type: | Thesis (Other) |
|---|---|
| Additional Information: | RSMt 620.192 Bak p-1 2019 |
| Uncontrolled Keywords: | Degradation, Molecular Weight, Poly(Lactic Acid), Ring – Opening Polymerization, Water Absorption, Zing Acetate. |
| Subjects: | T Technology > TP Chemical technology T Technology > TP Chemical technology > TP1140 Polymers T Technology > TP Chemical technology > TP248.3 Biochemical engineering. Bioprocess engineering |
| Divisions: | Faculty of Industrial Technology > Material & Metallurgical Engineering > 28201-(S1) Undergraduate Thesis |
| Depositing User: | Muhammad Bakhtiar |
| Date Deposited: | 29 Nov 2023 07:54 |
| Last Modified: | 29 Nov 2023 07:54 |
| URI: | http://repository.its.ac.id/id/eprint/64910 |
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