PRA-DESAIN PABRIK GARAM FARMASI DARI AIR LAUT DENGAN METODE MULTIPLE EFFECT

Diah, Diah Muslimawati and Novi, Novi Arimbi Diniari (2021) PRA-DESAIN PABRIK GARAM FARMASI DARI AIR LAUT DENGAN METODE MULTIPLE EFFECT. Project Report. [s.n.]. (Unpublished)

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Abstract

Garam farmasi merupakan garam Natrium Klorida yang memenuhi persyaratan Farmakope, buku resmi yang dikeluarkan oleh sebuah negara yang berisi standarisasi, panduan dan pengujian sediaan obat. Dalam industri farmasi, garam ini merupakan bahan baku yang banyak digunakan untuk produksi infus, pelarut vaksin, sirup, oralit, dll. Di Indonesia hanya ada 1 pabrik garam farmasi yang dikelola oleh PT. Kimia Farma. Dengan banyaknya kebutuhan garam farmasi Indonesia menyebabkan Indonesia mengimpor dari beberapa negara tetangga. Garam farmasi ini diolah dari bahan baku air laut dengan menggunakan metode multiple effect evaporator (MEE). Terdapat 5 tahapan yang harus dilakukan sebelum dihasilkan produk garam farmasi sesuai dengan standart (kemurnian 99%). Tahapan yang pertama dilakukan adalah tahap pemurnian. Bahan baku yang digunakan adalah air laut. Selanjutnya Larutan garam dari unit pemurnian dipekatkan untuk menaikkan konsentrasi larutan garam tersebut dengam menggunakan multiple effect evaporator hingga mencapai kondisi saturated brine. Larutan garam yang telah dipekatkan di triple effect evaporator kemudian dipompakan menuju vacuum pan crystallizer V-220. Keluaran dari vacuum pan crystallizer yang berupa slurry dialirkan menuju centrifuge H-224 untuk proses pemisahan. Selanjutnya adalah proses pengendalian produk yakni kristal natrium klorida yang keluar iv dihaluskan menggunakan screen H-320 hingga ukuran 20-50 mesh. Untuk dapat mendirikan pabrik dengan kapasitas 11.000 ton/tahun dengan waktu operasi 330 hari kerja diperlukan total modal Modal Tetap (FCI) sebesar Rp. Rp 802.957.051.334,83; Modal Kerja (WCI) : Rp. 13.581.655.780,07; Modal Total (TCI) : Rp. 90.544.371.867,13 ; Biaya produksi per tahun (TPC) : Rp. 111.951.780.297,67 dengan estimasi penjualan Rp. 155.250.000.000 diperoleh nilai IRR 11,23% , POT 4,1 tahun, dan NPV sebesar 292.029.619.109 (positif) menunjukan bahwa pabrik garam farmasi ini layak untuk didirikan.
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Pharmaceutical salt is a sodium chloride salt that meets the requirements of Pharmacopoeia, an official book issued by a country that contains standardization, guidelines, and testing of drug preparations. In the pharmaceutical industry, this salt is a widely used raw material for the production of infusions, vaccine solvents, syrups, ORS, etc. In Indonesia, there is only 1 pharmaceutical salt factory managed by PT. Pharmaceutical Chemistry. With the large demand for Indonesian pharmaceutical salt, Indonesia imports from several neighboring countries. This pharmaceutical salt is processed from seawater by using themethod of multiple effect evaporator (MEE). 5 steps must be carried out before a pharmaceutical salt product is produced according to the standard (99% purity). The first stage is the purification stage. The raw material used in seawater. Furthermore, the salt solution from the purification unit is concentrated to increase the concentration of the salt solution using a multiple effect evaporator until it reaches a saturated brine condition. The concentrated salt solution in the triple effect evaporator is then pumped into the vacuum pan crystallizer V-220. The output from the vacuum pan crystallizer in the form of a slurry flows to the H-224 centrifuge for the separation process. Next is the production control process, namely the sodium chloride crystals that come out IV are smoothed using an H-320 screen to a size of 20-50 mesh. To be able to build a factory with a capacity of 11,000 tons/year with an operating time of 330 working days, a total Fixed Capital Capital (FCI) of Rp. Rp 802,957,051,334.83; Working Capital (WCI): Rp. 13,581,655,780.07; Total Capital (TCI): Rp. 90,544,371,867.13 ; Production cost per year (TPC): Rp. 111,951,780,297.67 with estimated sales of Rp. 155,250,000,000 obtained IRR 11.23%, POT 4.1 years, and NPV of 292,029,619,109 (positive) indicating that this pharmaceutical salt factory is feasible to establish.

Item Type:	Monograph (Project Report)
Uncontrolled Keywords:	NaCl, Multipple Effect Evaporator, Garam Farmasi
Subjects:	T Technology > TP Chemical technology > TP155.5 Chemical plants--Design and construction
Divisions:	Faculty of Industrial Technology and Systems Engineering (INDSYS) > Chemical Engineering > 24201-(S1) Undergraduate Thesis
Depositing User:	Novi Arimbi Diniari
Date Deposited:	19 Aug 2021 07:40
Last Modified:	20 Jun 2024 06:30
URI:	http://repository.its.ac.id/id/eprint/87239

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