Fabrikasi Glassy Carbon Electrode Termodifikasi Single Wall Carbon Nanotubes, Ketjen Black (KB), dan Nanopartikel Emas Sebagai Sensor Dopamin

Ardyansyah, Firman (2021) Fabrikasi Glassy Carbon Electrode Termodifikasi Single Wall Carbon Nanotubes, Ketjen Black (KB), dan Nanopartikel Emas Sebagai Sensor Dopamin. Masters thesis, Institut Teknologi Sepuluh Nopember Surabaya.

	Text 01211850012009-Master_Thesis.pdf - Accepted Version Restricted to Repository staff only until 1 October 2023. Download (1MB) | Request a copy
	Text 01211850012009-Master_Thesis.pdf Restricted to Repository staff only Download (1MB) | Request a copy

Abstract

Modifikasi Glassy Carbon Electrode (GCE) telah dilakukan dengan single wall carbon nanotubes (SWCNTs), ketjen black (KB), dan emas nanopartikel (AuNPs). GCE termodifikasi digunakan sebagai sensor dopamin dengan metode voltametri siklik. Hasil pengukuran sampel dopamin dalam bufer asetat 0,1 M pH 4 menunjukkan bahwa GCE termodifikasi SWCNTs, KB dan AuNPs menghasilkan arus puncak anodik lebih tinggi daripada GCE tanpa modifikasi. Limit deteksi dan sensitivitas elektroda termodifikasi terhadap larutan dopamin ditentukan dengan kurva kalibrasi yang merupakan plot variasi konsentrasi terhadap arus puncak anodik. Limit deteksi dan sensitivitas untuk larutan dopamin berturut-turut sebesar 0,4914 µM dan 52,1196 μA mm-2 μM-1. Uji interferensi dilakukan dengan menguji respons GCE termodifikasi terhadap larutan asam urat, asam askorbat, glukosa, dan urea dalam 3 variasi pH elektrolit yaitu dengan bufer asetat 0,1 M pH 4, bufer fosfat 0,1 M pH 7, dan bufer fosfat 0,1 M pH 10. Selektivitas sensor terbaik diperoleh pada pengujian dengan bufer asetat 0,1 M pH 4 karena hanya dopamin yang memunculkan arus puncak oksidasi dan reduksi. Pengujian kinerja elektroda termodifikasi dilakukan dengan variasi laju pemindaian dan diperoleh hasil bahwa interaksi antara elektroda dengan larutan uji dikontrol oleh proses difusi.
================================================================================================
Glassy Carbon Electrode (GCE) has been modified with single wall carbon nanotubes (SWCNT), ketjen black (KB), and gold nanoparticles (AuNPs). The modified electrode was used as a dopamine sensor with the cyclic voltammetry method. The measurement results of dopamine samples in acetate buffer 0.1 M pH 4 showed that GCE modified SWCNT, KB and AuNPs could produce higher anodic peak currents than GCE without modification. The detection limit and the sensitivity of the modified electrode to dopamine solution were determined using a calibration curve which plots the concentration variation to the anodic peak current. The detection and sensitivity limits for dopamine solutions were 0.4914 µM and 52.1196 µA mm-2 µM-1, respectively. The interference test was carried out by testing the modified GCE response to a solution of uric acid, ascorbic acid, glucose, and urea in 0.1 M acetate buffer pH 4, 0.1 M phosphate buffer pH 7, and 0.1 M phosphate buffer pH 10. The best sensor selectivity obtained on testing using 0.1 M acetate buffer pH 4 because only dopamin raise oxidation and reduction currents. The modified electrode performance test was carried out by varying the scan rate. The results showed that the diffusion process controlled the interaction between the electrodes and the test solution.

Item Type:	Thesis (Masters)
Uncontrolled Keywords:	Sensor Elektrokimia, Glassy Carbon Electrode, Dopamin, Single Wall Carbon Nanotubes, Ketjen Black, Natrium Kolat
Subjects:	Q Science > QD Chemistry > QD75.2 Chemistry, Analytic
Divisions:	Faculty of Science and Data Analytics (SCIENTICS) > Chemistry > 47101-(S2) Master Thesis
Depositing User:	Firman Ardyansyah
Date Deposited:	20 Aug 2021 07:29
Last Modified:	20 Aug 2021 07:29
URI:	http://repository.its.ac.id/id/eprint/87905

Actions (login required)

View Item