Sintesis dan Karakterisasi Ligan Hidrazon Berbasis Benzohidrazida dan Benzaldehid

Alam, Yusuf Syahril (2021) Sintesis dan Karakterisasi Ligan Hidrazon Berbasis Benzohidrazida dan Benzaldehid. Undergraduate thesis, Institut Teknologi Sepuluh Nopember.

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Abstract

Empat ligan hidrazon (L1-L4) berbasis benzohidrazida dan turunan benzaldehid berhasil disintesis dengan rendemen sebesar 26,229% – 82,912%. Variasi substituen yang disintesis yaitu –H, –CH3, –NO2, dan –Br. Hasil KLT menunjukkan bahwa produk sudah satu noda, bersifat nonpolar dimana nilai Rf berkisar 0,7-0,767. Urutan kepolaran senyawa yaitu L1 > L3 > L2 > L4. Karakterisasi FTIR menunjukkan keempat senyawa terdapat puncak di bilangan gelombang 3159 – 3223; 3004 – 3060; 1639-1643; dan 1557-1578 cm-1 yang mengindikasikan ikatan –NH, –Csp2 aromatik, –C=O, dan –C=N. Pada analisis UV-Vis λmax keempat senyawa berada di range 280-302 nm yang menandakan transisi n→π*, selain itu terdapat dua puncak moderat yang menandakan transisi π→π* dari benzena. Pada proton NMR, terdapat tiga kelompok signal yaitu 11,78 – 12,18 ppm (1H, s), 8,44 – 8,84 ppm (1H, s), dan 7-8 ppm yang menjelaskan keberadaan –NH, CH=N, dan hidrogen benzena. Khusus untuk L2, terdapat puncak 2,41 ppm (3H,s). Tiga kelompok signal juga terdeteksi pada karbon NMR yaitu 163, 148, dan sekitar 130 ppm yang menandakan karbonil, imina, dan benzena. Karakterisasi MS menyebutkan bahwa massa molekul relatif senyawa L1, L2, L3, dan L4 masing-masing sebesar 224, 238, 269, dan 303 g/mol dimana sudah sesuai dengan senyawa target.
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Four hydrazone ligands (L1-L4) based on benzohydrazide and
benzaldehyde derivatives were successfully synthesized with yields of
26,229% – 82,912%. The synthesized substituent variations were –H, –
CH3, –NO2, and –Br. The TLC results showed that the product had one
spot, was nonpolar where the Rf value ranged from 0.7 to 0.767. The
order of polar compounds is L1 > L3 > L2 > L4. FTIR characterization
showed the four compounds in peaks at wave numbers 3159 – 3223;
3004 – 3060; 1639-1643; and 1557-1578 cm-1 which obtained –NH, –
Csp2 aromatic, –C=O, and –C=N. In UV-Vis analysis, the λmax of the four
compounds was in the range of 280-302 nm which indicated the n→π*
transition, besides that there were two moderate peaks indicating the
π→π* transition of benzene. In proton NMR, there are three signal
groups, namely 11.78 – 12.18 ppm (1H, s), 8.44 – 8.84 ppm (1H, s), and
7-8 ppm which explains the presence of –NH, CH= N, and hydrogen
benzene. Especially for L2, there is a peak of 2.41 ppm (3H,s). Three
signal groups were also detected on the NMR carbon, namely 163, 148,
and around 130 ppm indicating carbonyl, imine, and benzene. MS
characterization stated that the relative molecular masses of compounds
L1, L2, L3, and L4 were 224, 238, 269, and 303 g/mol, respectively,
which were in accordance with the target compound.

Item Type:	Thesis (Undergraduate)
Uncontrolled Keywords:	Ligan, Hidrazon, Benzohidrazida, dan Benzaldehid. Ligand, Hydrazone, Benzohydrazide, dan Benzaldehyde
Subjects:	Q Science > QD Chemistry > QD471 Chemical compounds - Structure and formulas
Divisions:	Faculty of Science and Data Analytics (SCIENTICS) > Chemistry > 47201-(S1) Undergraduate Thesis
Depositing User:	Yusuf Syahril Alam
Date Deposited:	21 Aug 2021 23:45
Last Modified:	21 Aug 2021 23:45
URI:	http://repository.its.ac.id/id/eprint/88569

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