Satriana, Erika (2022) Studi Performa dan Sifat Fatigue Material Injectable Silicone Rubber/Poly(Vinyl Alcohol)/ZrO2 Sebagai Kandidat Material Pengganti Nucleus Pulposus. Other thesis, Institut Teknologi Sepuluh Nopember.
![[thumbnail of 02511840000126-Undergraduate_Thesis.pdf]](http://repository.its.ac.id/style/images/fileicons/text.png) |
Text
02511840000126-Undergraduate_Thesis.pdf - Accepted Version Restricted to Repository staff only until 1 April 2024. Download (3MB) | Request a copy |
Abstract
Lower back pain (LBP) atau nyeri punggung bawah adalah gangguan kesehatan yang paling umum di antara orang dewasa yang dapat mengakibatkan rasa sakit kronis atau bahkan kecacatan. Menurut etiologinya, salah satu penyakit terkait LBP adalah degenerasi intervertebral disc (IVD). Sebagai salah satu cara pengobatan terhadap degenerasi IVD ini adalah pengisian suatu bagian bernama nucleus pulposus yang terdegradasi dengan suatu injectable material sebagai prosedur bedah minimal invasif. Tujuan dari penelitian ini adalah untuk menganalisis performa dan sifat fatigue material injectable silicone rubber/poly(vinyl alcohol) dengan tambahan material radiopak berupa zirkonium dioksida (ZrO2). Variasi yang digunakan dalam penelitian ini adalah komposisi ZrO2 yang ditambahkan ke dalam komposit sebesar 0.5, 1.5, dan 2%. Pada penelitian ini dilakukan beberapa karakterisasi, antara lain pengujian injectability, pengujian tarik, pengujian SEM-EDX, dan pengujian DMA. Dari hasil pengujian injectability didapatkan bahwa penambahan ZrO2 memperbesar gaya sebanyak 2 N untuk setiap variasi serta menambah waktu injeksi dari komposit. Penambahan ZrO2 akan mempengaruhi sifat tarik komposit dengan meningkatkan nilai modulus elastisitas, menurunkan yield strength, dan menurunkan tensile strength. Selain itu, penambahan ZrO2 juga dapat menurunkan ukuran pori sebesar 5% setiap variasi. Serta pengujian DMA dilakukan dengan hasil bahwa proses perendaman sampel pada Phosphate Buffer Saline akan menurunkan nilai storage modulus, loss modulus, dan tan delta. Variasi SR/PVA dengan penambahan 1.5% ZrO2 memenuhi persyaratan sifat injectability serta kriteria nilai modulus elastisitas yaitu sebesar 0.66 ± 0.05 MPa.
================================================================================================
Lower back pain (LBP) is the most common health disorder among adults that can result in chronic pain or even disability. According to its etiology, It can be observed by degeneration of the intervertebral disc (IVD). As one way of treatment is the filling of a part called the nucleus pulposus which has been degraded with an injectable material as a minimally invasive surgical procedure. The purpose of this study was to analyze the performance and fatigue properties of injectable silicone rubber /poly(vinyl alcohol) material with the addition of radiopaque material in the form of zirconium dioxide (ZrO2). The variation was 0.5, 1.5, and 2%. In this study, several tests were conducted, including injectability testing, tensile testing, SEM-EDX testing, and DMA testing. From the results of injectability testing it was found that the addition of ZrO2 increased the force by 2 N for each variation and increased the injection time of the composite. The addition of ZrO2 will affect the tensile properties of the composite by increasing the modulus of elasticity, decreasing yield strength, and decreasing tensile strength. Besides that, the addition of ZrO2 can also reduce the size of the pore by 5% each variation. The DMA testing carried out with the result that the sample immersion process in Phosphate Buffer Saline will reduce the value of storage modulus, loss modulus, and tan delta. The SR/PVA hydrogel with the addition of 1.5% ZrO2 meets the requirements of injectability properties and the modulus elasticity value criteria which is 0.66 ± 0.05MPa.
| Item Type: | Thesis (Other) |
|---|---|
| Uncontrolled Keywords: | Degenerasi IVD, Degeneration of IVD, Nucleus Pulposus, Silicone Rubber, PVA, ZrO2 |
| Subjects: | Q Science > QC Physics > QC173.4.C63 Composite materials T Technology > T Technology (General) > TA404 Materials--Biodegradation T Technology > TP Chemical technology > TP1140 Polymers |
| Divisions: | Faculty of Industrial Technology and Systems Engineering (INDSYS) > Material & Metallurgical Engineering > 28201-(S1) Undergraduate Thesis |
| Depositing User: | Erika Satriana |
| Date Deposited: | 03 Feb 2022 08:14 |
| Last Modified: | 02 Nov 2022 02:31 |
| URI: | http://repository.its.ac.id/id/eprint/92721 |
Actions (login required)
 |
View Item |