Bukhori, Muhamad Yusuf (2022) Analisis Morfologi Dan Performa Antibakteri Komposit Nanofiber Quantum Dots Cuins2 Dan Cuins2/Tio2. Other thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Komposit nanofiber Quantum Dots telah diteliti memiliki kemampuan antibakteri yang baik. Namun, penelitian mengenai karakteristik dan interaksi permukaan bakteri pada komposit Nanofiber/Quantum Dots masih jarang ditemui. dalam hal ini, perlu adanya studi tentang karakteristik permukaan dan memahami hubungannya antara permukaan nanofiber Quantum Dots terhadap interaksi dengan bakteri gram positif dan gram negatif. Penelitian ini bertujuan untuk menggunakan CuInS₂ dan CuInS₂/TiO₂ Quantum Dots sebagai material antimikroba yang disintesis dengan metode Wet Chemical yang selanjutnya diimplan ke campuran nanofiber PAN/PCL dengan menggunakan metode electrospinning. Variasi Quantum Dots CuInS2 dan CuInS2/TiO2 dengan konsentrasi 1,1 dan 15 ppm digunakan pada tiap varian diobservasi dan parameter analisis diameter fiber, surface roughness, hidrofobisitas, surface charge dan porositas. Hasil Pengujian SEM menunjukkan hasil diameter yang terbentuk dengan nilai terbesar 606.122 nm untuk sampel NF CIS-15, dan nilai terendah pada 512.857 nm untuk sampel NF CISTO-15. Hasil pengujian AFM menunjukkan nilai kekasaran permukaan pada permukaan nanofiber dengan nilai terbesar yaitu 272,5 untuk NF CIS-15, dan nilai terendah yaitu 184,1 nm untuk NF CISTO-1,1. Nilai ukuran pori diketahui melalui pengujian BET dengan hasil nilai terbesar yaitu 111,18 nm untuk NF CISTO-1,1, dan terkecil yaitu 93,07 nm untuk NF CISTO-15. Surface wetability juga diuji dengan pengujian hidrofobisitas dengan hasil nilai sudut kontak 137,23° untuk NF CIS-1,1, nilai sudut kontak 143° untuk NF CIS-15, nilai sudut kontak 130,64° untuk sampel NF CISTO-1,1, dan nilai sudut kontak 135° untuk NF CISTO-15. Muatan permukaan diuji dengan zeta potensial dengan hasil nilai surface charged sebesar -36,60 mV untuk larutan CIS Quantum Dots, 12 mV untuk larutan CISTO Quantum Dots, -21,40 mV untuk larutan PAN/PCL/CIS, -6,27 mV untuk larutan PAN/PCL/CISTO dan -8,12 mV untuk larutan PAN/PCL. Hasil pengujian dihubungkan dengan hasil pengujian antibakteri pada semua sampel baik sampel Quantum Dots maupun sampel nanofiber. Pengujian antibakteri membuktikan bahwa penambahan konsentrasi Quantum Dots pada nanofiber menambah nilai efisiensi performa antibakteri. Hal ini selaras dengan morfologi yang dimiliki nanofiber membantu peningkatan performa antibakteri. Dari hasil pengujian juga diketahui penambahan TiO2 pada proses electrospinning mengakibatkan nilai konduktivitas naik sehingga terjadi kerapatan intensitas kerapatan muatan pada permukaan larutan yang dikeluarkan saat proses electrospinning. Dari penelitian ini, diketahui penambahan TiO2 membuat fabrikasi nanofiber menghasilkan morfologi yang lebih kecil dibandingkan Quantum Dots murni, namun meningkatkan efektivitas antibakterinya
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Quantum Dots nanofiber composites have been studied to have good antibacterial properties. However, research on the characteristics and surface interactions of bacteria on Nanofiber/Quantum Dots composites is still rare. In this case, it is necessary to study the surface characteristics and understand the relationship between the Quantum Dots nanofiber surface and the interaction with gram-positive and gram-negative bacteria. This study aims to use CuInS₂ and CuInS₂/TiO₂ Quantum Dots as antimicrobial materials synthesized by the Wet Chemical method which are then implanted into a PAN/PCL nanofiber mixture using the electrospinning method. Variations of Quantum Dots CuInS2 and CuInS2/TiO2 with concentrations of 1.1 and 15 ppm used for each variant were observed and parameters for analyzing fiber diameter, surface roughness, hydrophobicity, surface charge and porosity. The results of the SEM test showed that the diameter formed was the highest at 606,122 nm for the NF CIS-15 sample, and the lowest value at 512,857 nm for the NF CISTO-15 sample. The AFM test results showed the surface roughness value on the nanofiber surface with the highest value being 272.5 for NF CIS-15, and the lowest value being 184.1 nm for NF CISTO-1.1. The value of the pore size was known through BET testing with the largest value being 111.18 nm for NF CISTO-1.1, and the smallest being 93.07 nm for NF CISTO-15. Surface wettability was also tested by hydrophobicity testing with a contact angle value of 137.23° for NF CIS-1.1, a contact angle value of 143° for NF CIS-15, a contact angle value of 130.64° for sample NF CISTO-1.1 , and a contact angle value of 135° for NF CISTO-15. The surface charge was tested with zeta potential with a surface charged value of -36.60 mV for CIS Quantum Dots solution, 12 mV for CISTO Quantum Dots solution, -21.40 mV for PAN/PCL/CIS solution, -6.27 mV for PAN/PCL/CISTO solution and -8.12 mV for PAN/PCL solution. The test results were associated with the results of the antibacterial test on all samples, both Quantum Dots samples and nanofiber samples. Antibacterial testing proves that the addition of Quantum Dots concentration on nanofiber increases the efficiency value of antibacterial performance. This is in line with the morphology of the nanofiber which helps to increase antibacterial performance. From the test results it was also known that the addition of TiO2 in the electrospinning process resulted in an increase in the conductivity value resulting in a density of charge density on the surface of the solution released during the electrospinning process. From this study, it is known that the addition of TiO2 makes nanofiber fabrication produce a smaller morphology than pure Quantum Dots, but increases its antibacterial effectiveness
| Item Type: | Thesis (Other) |
|---|---|
| Additional Information: | RSMt 620.115 Buk a-1 2022 |
| Uncontrolled Keywords: | Antibakteri, Efisiensi, Nanofiber, Quantum Dots |
| Subjects: | Q Science > QC Physics > QC173.4.C63 Composite materials |
| Divisions: | Faculty of Industrial Technology and Systems Engineering (INDSYS) > Material & Metallurgical Engineering > 28201-(S1) Undergraduate Thesis |
| Depositing User: | EKO BUDI RAHARJO |
| Date Deposited: | 18 Jan 2023 03:32 |
| Last Modified: | 18 Jan 2023 03:32 |
| URI: | http://repository.its.ac.id/id/eprint/95454 |
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