Andrianingsih, Agnes Meike (2023) Analisis Pengaruh Penambahan 3-Aminopropyltriethoxysilane Dan Variasi Komposisi Filler Pada Peek/Β-Tcp/Ha Terhadap Sifat Mekanik, Morfologi, Dan Biodegradasi Untuk Aplikasi Spinal Implant. Other thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Komposit memiliki peran penting pada berbagai bidang industri, salah satu contohnya adalah pada bidang medis. Salah satu aplikasi komposit di bidang medis adalah penggunaannya pada spinal implant. Material yang memiliki potensi untuk dikembangkan sebagai bahan spinal implant adalah polyether-ether-ketone (PEEK). Pada penelitian ini telah dilakukan pembuatan komposit berbasis PEEK/β-TCP/HA dengan modifikasi silane coupling agent untuk mendapatkan sifat mekanik, resorpsi serta interfacial strength yang lebih baik. Penelitian ini menggunakan empat variasi komposisi filler yaitu 100% β-TCP, 70% β-TCP:30% HA, 30% β-TCP:70%HA, dan 100%HA. Selain itu persentase coupling agent juga divariasikan menjadi 0%, 1%, 3%, dan 5%. Pengujian yang dilakukan meliputi Scanning Electron Microscope (SEM), Fourier Transform Infra Red (FTIR), pengujian tekan, dan pengujian weight loss. Dari hasil penelitian menunjukkan bahwa penambahan persentase coupling agent dapat meningkatkan sifat mekanik, morfologi, serta dapat menurunkan laju degradasi dari sampel. Pada variasi penambahan persentase coupling agent, sampel dengan kandungan 5% menjadi kandidat paling baik dengan nilai compressive strength sebesar 35,59 MPa dan waktu degradasi selama 26 bulan. Selain itu, kombinasi filler antara β-TCP dan HA juga dapat memperbaiki sifat mekanik serta membantu regenerasi tulang menjadi lebih optimal. Pada variasi komposisi filler sampel dengan komposisi 30% β-TCP:70% HA merupakan kandidat paling baik yang memenuhi standar penyembuhan tulang yaitu dengan nilai compressive strength sebesar 31,35 MPa serta waktu degradasi selama 27,6 bulan
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Composites have an important role in various industrial fields, one example is in the medical field. One of the applications of composites in the medical field is its use in spinal implants. Materials that have the potential to be developed as spinal implant materials are polyether-ether-ketone (PEEK). In this research, a PEEK/β-TCP/HA-based composite was made with a modified silane coupling agent to obtain better mechanical, resorption and interfacial strength properties. This study used four variations of filler composition, namely 100% β-TCP, 70% β-TCP:30% HA, 30% β-TCP:70%HA, and 100% HA. In addition, the percentage of coupling agent is also varied to 0%, 1%, 3% and 5%. Tests carried out included Scanning Electron Microscope (SEM), Fourier Transform Infra Red (FTIR), compression testing, and weight loss testing. From the results of the study showed that the addition of the percentage of coupling agent can improve the mechanical properties, morphology, and can reduce the rate of degradation of the sample. In the variation of the addition of the percentage of coupling agent, the sample with a content of 5% is the best candidate with a compressive strength value of 35.59 MPa and a degradation time of 26 months. In addition, the filler combination between β-TCP and HA can also improve mechanical properties and help bone regeneration to be more optimal. In the variation of the sample filler composition with a composition of 30% β-TCP:70% HA is the best candidate that meets the standard of bone healing, with a compressive strength value of 31.35 MPa and a degradation time of 27.6 months
| Item Type: | Thesis (Other) |
|---|---|
| Additional Information: | RSMt 617.95 And a-1 2023 |
| Uncontrolled Keywords: | Composite, Coupling Agent, Degradation, Spinal Implant, Coupling Agent, Degradasi, Komposit, Spinal Implant. |
| Subjects: | R Medicine > R Medicine (General) > R857.M3 Biomedical materials. Biomedical materials--Testing. T Technology > T Technology (General) > TA404 Materials--Biodegradation |
| Divisions: | Faculty of Industrial Technology and Systems Engineering (INDSYS) > Material & Metallurgical Engineering > 28201-(S1) Undergraduate Thesis |
| Depositing User: | Agnes Meike Andrianingsih |
| Date Deposited: | 06 Feb 2023 07:05 |
| Last Modified: | 25 Aug 2023 08:25 |
| URI: | http://repository.its.ac.id/id/eprint/96300 |
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