Rachmawati, Widia (2018) Konjac Glucomannan-Agar-Gliserin Sebagai Biopolimer Hard Capsule. Masters thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Konjac glukomannan (KGM) dari umbi porang (Amorphophallus oncophyllus) dikembangkan sebagai bahan baku pembuatan biopolimer hard capsule. Biopolimer KGM (konjac glukomannan), KGMA (konjac glukomannan – agar-agar) dan KGMAG (konjac glukomannan – agar-agar – gliserin) digunakan untuk memperoleh formulasi biopolimer hard capsule yang optimum. Campuran KGM 1,4% (b/v), agar – agar (0,75% b/v) dan gliserin (0.25% v/v) merupakan formulasi yang tepat untuk mendapatkan biopolimer hard capsule dengan sifat mekanik yang baik. Biopolimer hard capsule yang dihasilkan diuji sifat mekanik (tensile strength dan elongation break), uji swelling, degradasi biopolimer terhadap pengaruh pH (pH : 1,2 ; 4,5; dan 6,8), FTIR dan SEM. Hasil uji sifat mekanik menunjukkan biopolimer hard capsule memiliki tensile strength 42.28 Mpa dan 43.68% elongation break. Biopolimer hard capsule yang optimum memiliki kemampuan swelling sampai 85% dan dapat terdegradasi pada pH 1,2 (pH lambung). ============ Konjac glukomannan (KGM) from porang bulb (Amorphophallus oncophyllus) was developed as a raw material for making hard capsule biopolymer. The biopolymer of KGM (konjac glucomannan), KGMA (konjac glucomannan - agar) and KGMAG (Konjac glucomannan - agar - glycerin) were prepared to obtain optimum hard capsule biopolymer formulations. The KGM mixture of 1.4% (w / v), agar-agar (0.75% w / v) and glycerin (0.25% v / v) were the best formulation for hard capsule biopolymers with good mechanical properties. The resulting hard capsule biopolymer was evaluated the mechanical properties (tensile strength and elongation break), swelling test, biopolymer degradation to the effect of pH (pH: 1.2; 4.5 and 6.8), FTIR and SEM. The test results of its character showed that hard capsule biopolymer had tensile strength 42.28 MPa and 43.68% elongation extension. The optimum hard capsule biopolymer had swelling ability of up to 85% and could be degraded at pH 1.2 (gastric pH).
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | RTKi 547.7 Rac k |
| Uncontrolled Keywords: | konjac glukomannan; biopolimer; hard capsule; tensile strength; degradasi polimer |
| Subjects: | Q Science Q Science > QD Chemistry Q Science > QP Physiology > QP801.B69 Biopolymers |
| Divisions: | Faculty of Natural Science > Chemistry > 47101-(S2) Master Thesis |
| Depositing User: | Rachmawati Widia |
| Date Deposited: | 30 Apr 2018 03:35 |
| Last Modified: | 22 Jul 2020 07:49 |
| URI: | http://repository.its.ac.id/id/eprint/51017 |
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