Sistem Pengujian Pompa pada Mesin Hemodialisis ITS

Muhammad, Fathin (2024) Sistem Pengujian Pompa pada Mesin Hemodialisis ITS. Other thesis, Institut Teknologi Sepuluh Nopember.

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Abstract

Penyakit ginjal kronis (PGK) merupakan kondisi gangguan ginjal yang merujuk pada hilangnya fungsi ginjal dalam jangka panjang. Salah satu tindakan untuk menangani PGK adalah dengan hemodialisis atau cuci darah. Mesin hemodialisis berbasis mikrokontroler yang dikembangkan oleh ITS telah berhasil diujicobakan dalam skala laboratorium. Pada penelitian sebelumnya, mesin ini telah diuji menggunakan cairan dialisat dan darah buatan. Namun, pengujian belum dilakukan dengan darah asli atau cairan heparin, yang masing-masing memiliki karakteristik berbeda. Penelitian ini bertujuan untuk mengembangkan sistem pengujian pompa pada mesin hemodialisis dan menguji kinerjanya dengan darah. Pengujian dilakukan dalam tiga tahap: pertama, pengujian pompa cairan asam, basa, dan air reverse osmosis (RO) dengan variasi tegangan untuk melihat pengaruhnya terhadap aliran dan tekanan; kedua, pengujian pompa dialisat pada proses preparation; dan ketiga, pengujian pompa pada proses ultrafiltrasi menggunakan darah.Hasil penelitian menunjukkan bahwa peningkatan tegangan sebesar 0,5 Volt pada pompa mempengaruhi kecepatan aliran dan tekanan yang dihasilkan. Untuk memenuhi kebutuhan sistem, kecepatan aliran pompa pencampuran diatur pada 500 ml/menit dengan tegangan masing-masing pompa: 1,819 Volt untuk pompa RO, 1,844 Volt untuk pompa asam, dan 2,183 Volt untuk pompa basa. Tekanan yang dihasilkan diatur agar tidak melebihi rentang -400 hingga 350 mmHg. Pada aliran 500 ml/menit, pompa RO menghasilkan tekanan 29 mmHg, pompa asam 27 mmHg, dan pompa basa 25 mmHg. Selama proses preparation, kecepatan aliran yang dihasilkan berkisar antara 404,50 hingga 667,17 ml/menit dengan tekanan antara 12,53 hingga 24,98 mmHg. Pada proses ultrafiltrasi, kecepatan aliran pompa dialisat berkisar antara 397,061 hingga 501,15 ml/menit, dan tekanan yang dihasilkan berada dalam batas aman penggunaan dialiser (-400 hingga 350 mmHg). Namun, tekanan dialisat perlu diatur agar tidak melebihi tekanan darah untuk mencegah pecahnya membran.
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Chronic kidney disease (CKD) refers to a condition where the kidneys lose function over a long period. One of the treatments for CKD is hemodialysis. A microcontroller-based hemodialysis machine developed by ITS has been successfully tested on a laboratory scale. In previous research, this machine was tested using dialysate fluid and artificial blood. However, testing has not been done with real blood or heparin fluid, each of which has different characteristics. This study aims to develop a pump testing system for the hemodialysis machine and evaluate its performance with blood. Testing was conducted in three stages: first, testing the acid, base, and (reverse osmosis) RO water pumps with varying voltages to observe their effects on flow and pressure; second, testing the dialysate pump during the preparation process; and third, testing the pump during the ultrafiltration process using blood. The results showed that a 0.5 Volt increase in pump voltage affected the flow rate and pressure produced. To meet the systems requirements, the mixing pump flow rate was set at 500 ml/min with the following pump voltages: 1.819 Volt for the RO pump, 1.844 Volt for the acid pump, and 2.183 Volt for the base pump. The generated pressure was controlled to not exceed the range of -400 to 350 mmHg. At a flow rate of 500 ml/min, the RO pump produced a pressure of 29 mmHg, the acid pump 27 mmHg, and the base pump 25 mmHg. During the preparation process, the flow rate ranged from 404.50 to 436.46 ml/min, with pressures between 12.53 and 24.98 mmHg. In the ultrafiltration process, the dialysate pump flow rate ranged from 397.061 to 501.15 ml/min, and the generated pressure was within the safe limits for dialyzer use (-400 to 350 mmHg). However, the dialysate pressure needs to be controlled so that it does not exceed the blood pressure to prevent membrane rupture.

Item Type:	Thesis (Other)
Uncontrolled Keywords:	Efisiensi, Kecepatan Aliran, Pompa, Tegangan, Tekanan Eficiency, Flowrate, Pressure, Pump, Voltage
Subjects:	R Medicine > RC Internal medicine > RC901.7.H45 Hemodialysis.
Divisions:	Faculty of Intelligent Electrical and Informatics Technology (ELECTICS) > Biomedical Engineering > 11410-(S1) Undergraduate Thesis
Depositing User:	Fathin Muhammad
Date Deposited:	12 Aug 2024 04:45
Last Modified:	12 Aug 2024 04:45
URI:	http://repository.its.ac.id/id/eprint/113483

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