Faradela, Dewinta Aulia and Rasphian, Cholifia A'ang (2025) Pengaruh Rasio Konsentrasi Bovine Hydroxyapatite/Chitosan/Hyaluronic Acid dan Waktu Deposisi Pada Pelapisan Stainless Steel 316L Menggunakan Metode Deposisi Elektroforesis Terhadap Antibakteri dan Biokompatibilitas Implan Tulang. Other thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Fraktur tulang adalah masalah kesehatan global dengan lebih dari 455 juta kasus sejak tahun 2019 yang umumnya ditangani dengan pemasangan implan tulang. Implan Stainless Steel 316L (SS316L) sering digunakan karena ketahanan korosinya, namun memiliki kelemahan seperti pelepasan ion logam beracun, risiko infeksi akibat biofilm bakteri, dan keterbatasan osseointegrasi. Penelitian ini bertujuan meningkatkan sifat antibakteri dan biokompatibilitas SS316L melalui pelapisan Bovine Hydroxyapatite/Chitosan/Hyaluronic Acid (HAp/CS/HA) menggunakan metode deposisi elektroforesis (EPD). Metode EPD dipilih karena memiliki biaya rendah, fleksibilitas tinggi, serta kemampuan menghasilkan lapisan seragam dan terkendali pada permukaan kompleks. Pendekatan ini diharapkan meningkatkan performa implan dengan ketahanan korosi lebih baik dan efek antibakteri yang lebih efektif.
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Bone fracture is a global health problem with more than 455 million cases since 2019 which is commonly treated with bone implants. Stainless Steel 316L (SS316L) implants are often used because of their corrosion resistance, but SS316L have disadvantages such as the release of toxic metal ions, the risk of infection due to bacterial biofilms, and limited osseointegration. This study aims to improve the antibacterial properties and biocompatibility of SS316L through Bovine Hydroxyapatite/Chitosan/Hyaluronic Acid (HAp/CS/HA) coating using the electrophoretic deposition (EPD) method. The EPD method was chosen because it has low cost, high flexibility, and the ability to produce uniform and controlled layers on complex surfaces. This approach is expected to improve implant performance with better corrosion resistance and more effective antibacterial effects.
| Item Type: | Thesis (Other) |
|---|---|
| Uncontrolled Keywords: | Deposisi Elektroforesis, Hidroksiapatit, Pelapisan Implan Coating Implant, Electrophoresis Deposition, Hydroxyapatite |
| Subjects: | Q Science > QD Chemistry > QD115 Electrochemical analysis R Medicine > R Medicine (General) > R857.M3 Biomedical materials. Biomedical materials--Testing. T Technology > TP Chemical technology > TP1140 Polymers |
| Divisions: | Faculty of Vocational > 24305-Industrial Chemical Engineering Technology |
| Depositing User: | Dewinta Aulia Faradela |
| Date Deposited: | 04 Aug 2025 03:15 |
| Last Modified: | 04 Aug 2025 03:15 |
| URI: | http://repository.its.ac.id/id/eprint/125034 |
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