Fariana, Pitut (2011) Analisis Stabilitas Dan Pengendalian Optimal Pada Terapi Obat Dalam Pengobatan HIV. Other thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Highly Active Antiretroviral Theraphy (HAART) Adalah metode pengobatan yang dilakukan pada penderita HIV yang bertujuan untuk memperlambat perkembangan infeksi HIV menjadi AIDS. Terapi ini dilakukan dengan cara menggabungkan 2 atau 3 obat antiretroviral. Pada model dinamik HIV ini dilakukan pengendalian optimal dengan meminimumkan fungsi tujuan untuk meningkatkan konsentrasi set CD4+T dan mengurangi pengaruh efek samping obat yang diberikan terhadap tubuh. Pada Tugas Akhir ini dibahas pengendalian optimal dari gabungan terapi menggunakan metode Pontryagin Minimum Principle untuk mendapatkan penyelesaian yang optimal. Hasil analisa menunjukkan bahwa kontrol obat yang diberikan dapat meningkatkan konsentrasi sel CD4+ T
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Highly Active Antiretroviral Therapy (HAART) is a treatment method used in HIV patients to slow the progression of HIV infection to AIDS. This therapy is carried out by combining two or three antiretroviral drugs. In this dynamic HIV model, optimal control is carried out by minimizing the objective function to increase the concentration of CD4+ T cells and reduce the side effects of the drugs administered to the body. This final project discusses optimal control of combined therapy using the Pontryagin Minimum Principle method to obtain an optimal solution. The analysis results show that the administered drug control can increase the concentration of CD4+ T cells
Item Type: | Thesis (Other) |
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Additional Information: | RSMa 519.642 Far a-1 2011 (weding) |
Uncontrolled Keywords: | HIV/AIDS, Optimal Control, Prinsip Minimum Pontryagin; HIV I AIDS, Optimal Control, Pontryagin Minimum Principle |
Subjects: | Q Science > QA Mathematics > QA276 Mathematical statistics. Time-series analysis. Failure time data analysis. Survival analysis (Biometry) |
Divisions: | Faculty of Mathematics and Science > Mathematics > 44201-(S1) Undergraduate Thesis |
Depositing User: | EKO BUDI RAHARJO |
Date Deposited: | 18 Sep 2025 03:45 |
Last Modified: | 18 Sep 2025 03:45 |
URI: | http://repository.its.ac.id/id/eprint/128292 |
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