Potensi Ekstrak Bunga Kamboja Jepang (Adenium obesum) Sebagai Antibakteri Terhadap Pseudomonas aeruginosa Dan Enterococcus faecalis.

Jasman, Zamirza Amirul Zulhaq Putra (2022) Potensi Ekstrak Bunga Kamboja Jepang (Adenium obesum) Sebagai Antibakteri Terhadap Pseudomonas aeruginosa Dan Enterococcus faecalis. Other thesis, Institut Teknologi Sepuluh Nopember.

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Abstract

Bakteri Pseudomonas aeruginosa dan Enterococcus faecalis merupakan bakteri patogen yang dapat menyebabkan penyakit pada manusia, seperti infeksi saluran kemih (ISK) dan pneumonia. Penggunaan antibakteri dalam jangka waktu lama dapat menyebabkan bakteri mengalami resistensi terhadap antibakteri, menyebabkan efektivitas antibakteri menurun, sehingga diperlukan pencarian agen antibakteri baru. Pada penelitian ini, telah dilakukan ekstraksi bunga Kamboja Jepang (Adenium obesum) menggunakan metode maserasi dengan pelarut akuades, etil asetat, etanol dan aseton. Secara fitokimia, diketahui ekstrak bunga Kamboja Jepang (A. obesum) mengandung senyawa alkaloid, flavonoid, saponin, tannin, terpenoid dan glikosida yang berpotensi sebagai antibakteri. Ekstrak akuades bunga Kamboja Jepang menunjukkan diameter zona hambat terbesar dengan rata-rata zona hambat sebesar 12,50 ± 2,10 mm dan nilai Inhibititory Concentration 50 (IC50) sebesar 475,15 mg/mL terhadap bakteri P. aeruginosa dan 56,99 mg/mL terhadap E. faecalis. Pada penelitian ini, dapat disimpulkan bahwa ekstrak bunga Kamboja Jepang (A. obesum) memiliki potensi sebagai antibakteri terhadap P. aeruginosa dan E. faecalis.===================================================================================================================================
Pseudomonas aeruginosa and Enterococcus faecalis are pathogenic bacteria that can cause diseases in humans, such as urinary tract infections (UTI) and pneumonia. The use of antibacterials in the long term can cause bacteria to experience resistance to antibacterials, causing the effectiveness of antibacterials to decrease, so it is necessary to search for new antibacterial agents. In this study, the Japanese Frangipani flower (Adenium obesum) was extracted using the maceration method with distilled water, ethyl acetate, ethanol and acetone as solvents. Phytochemically, it is known that the Cambodian Japanese flower extract (A. obesum) contains alkaloids, flavonoids, saponins, tannins, terpenoids and glycosides that have the potential as antibacterial. The aquades extract of Japanese Frangipani flowers showed the largest diameter of the inhibition zone with an average inhibition zone of 12.50 ± 2.10 mm and an Inhibitory Concentration 50 (IC50) value of 475,15 mg/mL against P. aeruginosa bacteria and 56.99 mg/mL against E. faecalis. In this study, it can be concluded that the Japanese Frangipani flower extract (A. obesum) has potential as an antibacterial against P. aeruginosa and E. faecalis.

Item Type:	Thesis (Other)
Additional Information:	RSKi 579.37 Jas p-1 2022
Uncontrolled Keywords:	Pseudomonas aeruginosa, Enterococcus faecalis, Adenium obesum, ekstraksi maserasi, antibakteri. Pseudomonas aeruginosa, Enterococcus faecalis, Adenium obesum, maceration extraction, antibacterial.
Divisions:	Faculty of Science and Data Analytics (SCIENTICS) > Chemistry > 47201-(S1) Undergraduate Thesis
Depositing User:	Mr. Marsudiyana -
Date Deposited:	06 May 2026 04:49
Last Modified:	06 May 2026 04:49
URI:	http://repository.its.ac.id/id/eprint/133012

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