Pakpahan, grace lamria (2022) Pengkuran Kadar Hematokrit Untuk Menghitung Viskositas Darah Dan Perubahan Volume Darah Selama Hemodialisis. Other thesis, Institut Teknologi Sepuluh Nopember.
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Abstract
Penderita gangguan ginjal kronis (GGK) memerlukan penanganan berupa pengganti ginjal. Pengganti ginjal tersebut dapat dilakukan dengan hemodialisis. Hemodialisis bekerja dengan membentuk sebuah lingkungan yang sama dengan fungsi ginjal normal. Kontrol cairan berlebih menjadi kunci penting selama proses hemodialisis karena berhubungan dengan gangguan oksigenasi, kerusakan organ, lama waktu tinggal di rumah sakit, morbiditas, dan menjadi faktor risiko kematian pada GGK dan gagal ginjal. Selain itu, cairan berlebih juga menjadi penyebab umum timbulnya hipertensi dan dapat berkontribusi pada kardiovaskular yang buruk. Beberapa metode yang digunakan untuk mengukur cairan berlebih adalah pemantauan volume darah dan viskositas darah. Perubahan volume darah mengukur kadar hematokrit melalui pengukuran hemoglobin menggunakan teknik spektroskopi optik. Hematokrit merupakan variabel paling berpengaruh dalam menghitung viskositas darah. Penelitian ini memanfaatkan sensor photoplethysmography (PPG) untuk mengukur kadar hematokrit agar alat hemodialisa dapat melakukan perhitungan viskositas darah dan pemantauan perubahan volume darah. Pengukuran kadar hematokrit membutuhkan rasio komponen AC dan DC dari sinyal LED yang dimiliki sensor. Sinyal LED tersebut dilakukan proses pengolahan sinyal sehingga komponen AC dan DC tiap sinyal LED ditemukan. Komponen AC dan DC dapat ditemukan melalui pendekatan garis lurus. Setelah itu, kadar hemoglobin dihitung, kemudian kadar hematokrit dihitung. Berdasarkan pengujian kadar hemoglobin didapatkan presisi 94,63% dan akurasi 89,17%. Berdasarkan pengujian kadar hematokrit didapatkan presisi 94,63% dan akurasi 88,82%.
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Patients with chronic kidney disease (CKD) require treatment in the form of kidney replacement. Kidney replacement can be done with hemodialysis. Hemodialysis works by establishing an environment similar to normal kidney function. Control of excess fluid is an important key during the hemodialysis process because it is associated with impaired oxygenation, organ damage, length of hospitalization, morbidity, and is a risk factor for death in CKD and kidney failure. In addition, excess fluid is also a common cause of hypertension and can contribute to poor cardiovascular disease. Some of the methods used to measure excess fluid are monitoring blood volume and blood viscosity. Changes in blood volume measure hematocrit levels by measuring hemoglobin using optical spectroscopy techniques. Hematocrit is the most influential variable in calculating blood viscosity. This study uses a photoplethysmography (PPG) sensor to measure hematocrit levels so that the hemodialysis device can calculate blood viscosity and monitor changes in blood volume. Measurement of hematocrit levels requires the ratio of the AC and DC components of the sensor's LED signal. The LED signal is processed by signal processing so that the AC and DC components of each LED signal are found. The AC and DC components can be found using the straight-line approximation. After that, the hemoglobin level was calculated and then the hematocrit level was calculated. Based on the hemoglobin level test, the precision was 94.63% and the accuracy was 89.17%. Based on the hematocrit level test, the precision is 94.63% and the accuracy is 88.82%.
| Item Type: | Thesis (Other) |
|---|---|
| Additional Information: | RSB 617.461 059 Pak p-1 2022 |
| Uncontrolled Keywords: | hemodialisis, volume darah, viskositas darah, photoplethysmography, hematokrit. hemodialysis, blood volume, blood viscosity, photoplethysmography, hematocrit. |
| Subjects: | Q Science > QA Mathematics > QA75 Electronic computers. Computer science. EDP |
| Divisions: | Faculty of Intelligent Electrical and Informatics Technology (ELECTICS) > Biomedical Engineering > 11410-(S1) Undergraduate Thesis |
| Depositing User: | Mr. Marsudiyana - |
| Date Deposited: | 17 Jun 2026 08:35 |
| Last Modified: | 17 Jun 2026 08:35 |
| URI: | http://repository.its.ac.id/id/eprint/133865 |
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