Sintesis Hidroksiapatit dari Ca(OH)₂ Cangkang Keong Sawah (Pila ampullacea) dengan Variasi Laju Alir H₃PO₄ dan Suhu pada Reaktor Berpengaduk

Fariza, Fara and Rosidah, Alifiya Nur (2026) Sintesis Hidroksiapatit dari Ca(OH)₂ Cangkang Keong Sawah (Pila ampullacea) dengan Variasi Laju Alir H₃PO₄ dan Suhu pada Reaktor Berpengaduk. Other thesis, Institut Teknologi Sepuluh Nopember.

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Abstract

Hidroksiapatit (HAp) merupakan senyawa kalsium fosfat yang memiliki struktur dan komposisi mirip mineral utama penyusun tulang dan gigi manusia sehingga berpotensi untuk aplikasi biomedis. Salah satu sumber biomineral yang dapat dimanfaatkan adalah cangkang keong sawah (Pila ampullacea) yang kaya kalsium karbonat. Penelitian ini mensintesis HAp menggunakan metode presipitasi basah dalam reaktor berpengaduk dengan variasi laju alir H₃PO₄ (70, 120, dan 170
mL/menit) serta suhu reaktor (35, 50, dan 70 °C) untuk mengkaji pengaruhnya terhadap kinetika reaksi dan karakteristik HAp. Hasil analisis menunjukkan pembentukan HAp mengikuti kinetika reaksi orde satu dengan konstanta laju (k) 0,09 dan koefisien determinasi (R²) 0,98. Karakterisasi XRF menunjukkan kandungan CaO sebesar 99,96%, menandakan kemurnian tinggi sebagai sumber kalsium. Analisis FTIR mengonfirmasi terbentuknya gugus fosfat (PO₄³⁻), sedangkan pola difraksi XRD pada seluruh variasi mendekati standar hidroksiapatit JCPDS No.09-0432. Hasil SEM menunjukkan ukuran partikel rata-rata 594,23 nm pada laju alir 120 mL/menit dan suhu 50°C, serta 343,70 nm pada suhu 70°C dan laju alir70 mL/menit. Rasio Ca/P berdasarkan EDX berada pada kisaran 1,74–1,97.
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Hydroxyapatite (HAp) is a calcium phosphate compound with a structure and chemical composition similar to the primary mineral found in human bones and teeth, making it highly biocompatible and suitable for biomedical applications. One potential biomineral source is rice field snail (Pila ampullacea) shells, which are rich in calcium carbonate. In this study, HAp was synthesized using the wet precipitation method in a stirred reactor with varying H₃PO₄ flow rates (70, 120, and 170 mL/min) and reactor temperatures (35, 50, and 70°C) to investigate their effects on reaction kinetics and HAp characteristics. The results showed that HAp formation followed first-order reaction kinetics with a reaction rate constant (k) of 0.09 and a coefficient of determination (R²) of 0.98. XRF analysis revealed a CaO content of 99.96%, indicating high purity as a calcium source. FTIR confirmed the presence of phosphate (PO₄³⁻) functional groups, while XRD patterns for all experimental conditions closely matched the hydroxyapatite standard (JCPDS No. 09-0432). SEM analysis showed average particle sizes of 594.23 nm at a flow rate of 120 mL/min and 50°C, and 343.70 nm at 70°C and 70 mL/min. EDX analysis indicated a Ca/P ratio ranging from 1.74 to 1.97.

Item Type:	Thesis (Other)
Uncontrolled Keywords:	Hydroxyapatite, Rice Field Snail, Precipitation v, Reagent Rate, Hidroksiapatit, Keong Sawah, Laju Reagen, Presipitasi v
Subjects:	Q Science > QD Chemistry > QD481 Chemical structure. Q Science > QD Chemistry > QD502 Chemical kinetics Q Science > QD Chemistry > QD75.2 Chemistry, Analytic
Divisions:	Faculty of Vocational > 24305-Industrial Chemical Engineering Technology
Depositing User:	Fara Fariza
Date Deposited:	30 Jul 2026 00:53
Last Modified:	30 Jul 2026 00:53
URI:	http://repository.its.ac.id/id/eprint/138831

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