Dharmayani, Ni Komang Tri (2009) Bioaktivitas Antioksidan Senyawa 1,6-Dihidroksi-3` , 3` -Dimetil-2H- Piran (3,4)-5- Dimetil - But- 2enyl Santon Dan 4` -O -Metil - Katekin Dari Ekstrak Metanol Kulit Batang Garcinia Parvifolia (Asam Kandis). Masters thesis, Institut Teknologi Sepuluh November.
![[thumbnail of 1407201752-Master_thesis.pdf]](http://repository.its.ac.id/style/images/fileicons/text.png) |
Text
1407201752-Master_thesis.pdf Restricted to Repository staff only Download (27MB) |
Abstract
Dua senyawa fenolat telah berhasil diisolasi dari fraksi-fraksi ekstrak metanol kulit batang Garcinia parvifolia, yaitu 1,6-dihidroksi-3',3'-dimetil-2H-piran(3,4)-5-dimetil-but-2enil (1) dan 4'-O-metil katekin (2). Kedua senyawa tersebut didapatkan melalui maserasi menggunakan pelarut metanol dilanjutkan dengan fraksinasi menggunakan berbagai metode kromatografi. Penentuan struktur senyawa hasil isolasi dilakukan berdasarkan data spektroskopi UV, IR, ¹H-NMR dan ¹³C-NMR. Kedua senyawa tersebut menunjukkan aktivitas sebagai antioksidan terhadap radikal bebas 1,1-difenil-2-pikrilhidrazil (DPPH) dengan IC₅₀ berturut-turut 68,54 ppm dan 17,44 ppm.
======================================================================================================================================
Two phenolic compounds have been isolated from methanol extract of stem bark of Garcinia parvifolia: 1,6-dihydroxy-3',3'-dimethyl-2H-pyran (3,4)-5-dimethyl-but-2enyl xanthone (1) and 4'-O-methyl-catechin (2). Both of them were obtained by maseration using metanol solvent and followed by fractionated using chromatography methods. Elucidation structures were established on the basis spectroscopic studies (UV, IR, ¹H-NMR and ¹³C-NMR). Both of them exhibited radical scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical, which IC₅₀ for (1) and (2) are 68,54 ppm and 17,44 ppm.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | RTKi 613.286 Dha b |
| Uncontrolled Keywords: | Garcinia parvifolia Mig, senyawa fenolat, aktivitas antioksidan, DPPH, Garcinia parvifolia Miq, phenolic compounds, antioxidant activity, DPPH. |
| Subjects: | T Technology > TP Chemical technology > TP159.A5 Antioxidants |
| Divisions: | Faculty of Mathematics and Science > Chemistry > 47101-(S2) Master Thesis |
| Depositing User: | magang . |
| Date Deposited: | 05 Oct 2026 01:25 |
| Last Modified: | 05 Oct 2026 07:17 |
| URI: | http://repository.its.ac.id/id/eprint/145221 |
Actions (login required)
 |
View Item |